Diabetic Retinopathy (DR) is globally the primary cause of visual impairment and blindness in diabetic patients. Diabetic retinopathy occurs when the small blood vessels have a high level of glucose in the retina. That causes a change in the retina, which occur over a period of time in diabetics and cause the difficulties with vision. Regular screening is essential in order to detect the early ...

PURPOSE The pathogenesis of diabetic retinopathy (DR) is not fully understood. Clinical studies suggest that dyslipidemia is associated with the initiation and progression of DR. However, no direct evidence supports this theory. METHODS Immunostaining of apolipoprotein B100 (ApoB100, a marker of low-density lipoprotein [LDL]), macrophages, and oxidized LDL was performed in retinal sections fr...

PURPOSE Recent studies showed that immunological mechanisms were involved in the pathogenesis of diabetic retinopathy (DR). T-helper (Th) cells play an important role in chronic inflammatory disorders and autoimmune diseases. Whether Th cells participate in the pathogenesis of DR remains unclear. METHODS To evaluate the role of Th cells in the pathogenesis of type 2 diabetes mellitus with ret...

Background: This study aimed to determine the prevalence of Diabetic Retinopathy and find associated risk factors DR among known Type II DM patients. Materials Methods: A hospital-based cross-sectional single center was conducted patients with without in department Endocrinology a sample size 150 2018. Data were expressed as mean, standard deviation, proportions, Chi-Square, t-test test Binary ...

AIM To describe the design and preliminary results of the hospital based epidemiological study for diabetic retinopathy(HBESDR), an ongoing epidemiological study to estimate the prevalence of diabetic retinopathy(DR) and to elucidate the clinical, anthropometric, biochemical and any other risk factors associated with diabetic retinopathy. METHODS Totally 2000 diabetes will be recruited from t...

INTRODUCTION Diabetic retinopathy (DR) is one of the commonest causes of visual impairment and blindness in Nepal. OBJECTIVES The study aims to explore the prevalence, risk factors and awareness of DR among admitted diabetic patients. MATERIALS AND METHODS A non-interventional case series study was conducted among the inpatient diabetic cases referred for ophthalmic consultation. The patien...

BACKGROUND Diabetes and its related microvascular complications like diabetic retinopathy (DR) are showing increased prevalence in India. However, the magnitude of DR in rural population with diabetes needs exploration. AIM To estimate the prevalence and risk factors for the presence and severity of diabetic retinopathy in the self-reported rural population with diabetes. SETTINGS AND DESIG...

AIM AND METHODS Impaired eyesight and vision loss due to retinopathy are among the most feared complications in diabetic patients. As the number of diabetic patients is predicted to increase, a corresponding increase in the number of patients with diabetic retinopathy (DR) is also to be expected. This review is an update of the published literature pertaining to the epidemiology of DR. RESULT...

The pathogenesis of diabetic retinopathy (DR) is insufficiently understood and presumed to possibly involve inflammation and endothelial dysfunction. The aim of the study was to investigate the relationship between inflammation markers, other markers of endothelial dysfunction and anthropometric parameters and their association with DR in patients with type 2 diabetes, divided into three groups...

BACKGROUND Diabetic retinopathy (DR) is one of the leading causes of preventable blindness in low and middle income countries. In Nepal, there are less studies regarding DR and they too are limited around Kathmandu valley. This study was done to assess visual morbidity in patients with DR at a peripheral tertiary eye care center of Nepal. METHODS This was a prospective, hospital based, cross-...