Background: Monochorionic twin gestations are at increased risk of a variety of pregnancy complications which can be minimized by early antepartum diagnosis and management. This study is to assess the influence of chorionicity in twin pregnancies on perinatal outcome. Materials and Methods: A prospective study was conducted at, Institute of maternal and child health Calicut over a period of one...

OBJECTIVE To compare the prognostic value of fetal Doppler in dichorionic twins and singletons by measuring the interval between diagnosis of an abnormal Doppler flow and birth in fetuses who are small for gestational age (SGA). DESIGN Comparative retrospective study using a prospectively collected database. SETTING A level 3 maternity unit in France. POPULATION Fetuses from singleton and...

OBJECTIVE To examine the distribution of first-trimester biochemical markers of aneuploidy in twin pregnancies, and to assess whether there are differences in the distributions between monochorionic and dichorionic twins. METHODS Maternal serum-free beta-hCG and PAPP-A were measured between 11 + 0 and 13 + 6 weeks as part of a routine first-trimester screening program in conjunction with feta...

OBJECTIVE The aim is to describe the performance of first-trimester combined risk assessment in twin pregnancies. METHODS Maternal serum free beta-human chorionic gonadotrophin and pregnancy-associated plasma protein A (PAPP-A) were determined at 8 to 12 weeks and fetal nuchal translucency (NT) was measured at 11 to 13+6 weeks. The individual risk was estimated for each fetus using the combin...

Human cytomegalovirus (CMV) is the most common cause of viral intrauterine infection and fetal damage largely attributable to maternal primary infection. Most cases of congenital CMV infection in twins reported in the literature involved only 1 twin. We assessed the validity of polymerase chain reaction (PCR) and quantitative PCR on amniotic fluid (AF), at 21 to 22 weeks' gestation and at least...

There are only a few reports of fetal parvovirus infection in the circumstance of a twin pregnancy. We report a case of differential fetal infection following maternal parvovirus B19 infection in a dichorionic twin pregnancy culminating in a dual live-birth. A 32-year-old woman was diagnosed with parvovirus infection following exposure to her infected child at 19 weeks' gestation in a dichorion...

OBJECTIVE Fetal vessel thrombosis has been related to pregnancy complications and adverse neonatal outcomes in singleton pregnancies, but the clinical and pathologic characteristics of fetal thrombosis in twin pregnancy are still ill defined. METHODS To clarify the characteristics of fetal thrombosis in twins, we reviewed the histology slides and medical records of live-born infants of twin p...

Monochorionic fetuses are traditionally thought of as monozygotic (MZ), arising from a single embryo that splits during early embryogenesis. With rare exception, they typically exhibit the same genotype and the same gender. However, several recent reports have documented that monochorionicity does not always indicate monozygosity (Souter et al., 2003). At least 14 such cases have been reported ...

Objective. Our objective was to estimate degree and rate of discordant growth and its impact on perinatal outcome in dichorionic twin pregnancies conceived by in vitro fertilization (IVF) compared to those conceived spontaneously. Study Design. Growth discordance was defined as 90th percentiles for the study population. Adverse perinatal outcome was defined as 5-minute Apgar score <7 and/or adm...

OBJECTIVE To describe a new technique for embryo reduction (ER) in dichorionic triplet (DCT) pregnancies. METHODS In 22 DCT pregnancies, ER to dichorionic twins was carried out at 11.3-13.9 weeks' gestation by ultrasound-guided laser ablation of the pelvic vessels of one of the monochorionic twins. RESULTS Intrafetal laser was successfully carried out in all cases, but ultrasound examinatio...