In this work, a new framework and model for the digital generation and characterization of the microstructure of GDL materials with localized binder and polytetrafluoroethylene (PTFE) distributions were developed using 3D morphological imaging processing. This new generation technique closely mimics manufacturing processes and produces for the first time complete phase-differentiated (void, fib...

In this work, a new framework and model for the digital generation and characterization of the microstructure of gas diffusion layer (GDL) materials with localized binder and polytetrafluoroethylene (PTFE) distributions were developed using 3D morphological imaging processing. This new generation technique closely mimics manufacturing processes and produces complete phase-differentiated (void, ...

BACKGROUND Morphological examination of blood films remains the reference standard for malaria diagnosis. Supporting the skills required to make an accurate morphological diagnosis is therefore essential. However, providing support across different countries and environments is a substantial challenge. OBJECTIVE This paper reports a scheme supplying digital slides of malaria-infected blood wi...

Lee, Dennis Joseph Ph.D., Purdue University, May 2015. Computational Optical Imaging: Applications in Synthetic Aperture Imaging, Phase Retrieval, and Digital Holography. Major Professor: Andrew M. Weiner. Computational imaging has become an important field, as a merger of both algorithms and physical experiments. In the realm of microscopy and optical imaging, an important application is the p...

Image mosaicing has found a number of applications such as panoramic imaging, digital terrain mapping, ophthalmology and virtual microscopy. In this study, we present an automated mosaicing technique for generating virtual slides from microscope images. We carried out robust image feature matching and global geometric and radiometric parameter estimation. The input images were transformed using...

We present the implementation of a combined digital scanned light-sheet microscope (DSLM) able to work in the linear and nonlinear regimes under either Gaussian or Bessel beam excitation schemes. A complete characterization of the setup is performed and a comparison of the performance of each DSLM imaging modality is presented using in vivoCaenorhabditis elegans samples. We found that the use o...

We present a concept for a medical video server extended by a DICOM interface. DICOM conform security mechanisms will be integrated to enable secure Internet access. Especially digital stereoscopic video sequences (DSVS) that are relevant for surgery should be examined regarding clip length necessary for diagnosis and documentation and clip size manageable with today’s hardware. Methods for DSV...

The histology and the pathology clinical practice undergo a digital revolution. Essential change in laboratory practice - from classical light microscopes, thousands of glass specimens waiting on plates to a virtual microscope and onscreen diagnosis is right now. Currently there are more than 30 different systems for the Virtual Microscopy available on the market. However none of them is so ori...

Just as the microscope gave rise to the germ theory of disease and the remarkable advances that followed, our new-found ability to observe fine-grained information flows in electronic data portends a revolution in our understanding of information work. Managers who harness this new Digital Lens will uncover a wealth of insights into performance improvement for individuals, teams and organizatio...

Materials and methods: Helioseal and Delton Opaque fissure sealants were applied to pairs of contralateral mandibular second premolar teeth. Optically clear epoxy resin replicas were produced which were sequentially located and mounted within a defined plane. The replicas were transilluminated from below with diffused light, examined with a microscope and digital images captured. This allowed t...