نتایج جستجو برای: dihydropyrimidinone
تعداد نتایج: 69 فیلتر نتایج به سال:
An effective one-pot synthesis of dihydropyrimidinonoes in solvent free conditions using CuCl2 as an inexpensive and readily available reagent through Biginelli condensation reaction of aldehyde derivatives, 1,3-dicarbonyl compounds and urea is described. Excellent yields, short reaction times for formation of the products and simple work-up are attractive features of this green protocol.
In the present paper, synthesis of new series of 1,3,4oxadiazole derivatives incorporating substituted dihydropyrimidinone and chloroquinoline moieties 4(a-j) has been reported. All the synthesized compounds were characterized by FTIR, 1 H NMR and Mass spectroscopy. The compounds were screened for their in vivo anti-inflammatory activity by the carrageenan induced rat paw edema method and in vi...
The purpose of this study was to synthesize substituted 3,4-dihydropyrimidin-2(1H)ones (DHP) and to evaluate them for their antibacterial and antifungal activities. These compounds were synthesized by cyclocondensation reaction between substituted aromatic aldehyde i.e.,p-anisaldehyde, active methylene compounds (ethyl acetoacetate/acetylacetone), urea in the presence of CuCl2.2H2O and few drop...
Therapies to prevent onset and progression of pulmonary arterial pressure are not very effective yet. This study was designed to investigate the effects of a novel dihydropyrimidinone, ethyl 4-(4′-heptanoyloxyphenyl)-6methyl-3,4-dihydropyrimidin-2-one-5-carboxylate (H-DHPM) on pathogenesis of monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH). For the same purpose, rats were inje...
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