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Zirconium-89 is an emerging radionuclide for positron emission tomography (PET) especially for biomolecules with slow pharmacokinetics as due to its longer half-life, in comparison to fluorine-18 and gallium-68, imaging at late time points is feasible. Desferrioxamine B (DFO), a linear bifunctional chelator (BFC) is mostly used for this radionuclide so far but shows limitations regarding stabil...
Epidermal growth factor receptor (EGFR) is a transmembrane tyrosine kinase receptor, which is overexpressed in many types of cancer. The use of EGFR-targeting monoclonal antibodies and tyrosine-kinase inhibitors improves significantly survival of patients with colorectal, non-small cell lung cancer and head and neck squamous cell carcinoma. Detection of EGFR overexpression provides important pr...
The epidermal growth factor receptor (EGFR) is overexpressed in a number of malignant tumors and is a molecular target for several specific anticancer antibodies and tyrosine kinase inhibitors. The overexpression of EGFR is a predictive biomarker for response to several therapy regimens. Radionuclide molecular imaging might enable detection of EGFR overexpression by a non-invasive procedure and...
4.3. Reaction Mechanism 2373 4.4. Asymmetric Synthesis 2374 4.5. Outlook 2374 5. Alternating Polymerization of Oxiranes and CO2 2374 5.1. Reaction Outlines 2374 5.2. Catalyst 2376 5.3. Asymmetric Polymerization 2377 5.4. Immobilized Catalysts 2377 6. Synthesis of Urea and Urethane Derivatives 2378 7. Synthesis of Carboxylic Acid 2379 8. Synthesis of Esters and Lactones 2380 9. Synthesis of Isoc...
Application of the conventional X.500 approach to naming has heretofore, in the experience of the authors, proven to be an obstacle to the wide deployment of directory-enabled applications on the Internet. We propose a new directory naming plan that leverages the strengths of the most popular and successful Internet naming schemes for naming objects in a hierarchical directory. This plan can, w...
BACKGROUND Though overexpression of epidermal growth factor receptor (EGFR) in several forms of cancer is considered to be an important prognostic biomarker related to poor prognosis, clear correlations between biomarker assays and patient management have been difficult to establish. Here, we utilize a targeting directly followed by a non-targeting tracer-based positron emission tomography (PET...
This is a correction article CorrectionMuch to our regret we have to inform you about a mis-take/misprint in our recent article: Fruhmann Berger et al[1].In Table 1, the mean scores of the Glasgow Coma Scalereported for the stroke patient groups should read: Neg 14.6 (0.5);RBD 14.9 (0.3);LBD 14.2 (1.1).References1. Fruhmann Berger M, Proß RD, Ilg UJ, Karnath ...
In this short paper, we prove fixed point theorems for nonexpansive mappings whose domains are unbounded subsets of Banach spaces. These theorems are generalizations of Penot’s result in [Proc. Amer. Math. Soc., 131 (2003), 2371–2377].
2377 40th Lunar and Planetary Science Conference. [7] Ubachs W., I. Velchev, P. Cacciani 2000. Journal of Chemical Physics 113:547-560. 72nd Annual Meteoritical Society Meeting (2009) 5443.pdf
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