A discordant lymphoma occurs where 2 distinct histologic subtypes coexist in at least 2 separate anatomic sites. Histologic discordance is most commonly observed between the bone marrow (BM) and lymph nodes (LNs), where typically aggressive lymphoma is found in a LN biopsy with indolent lymphoma in a BM biopsy. Although the diagnosis of discordance relied heavily on histopathology alone in the ...

Using a qualitative monozygotic (MZ) twin differences design we explored whether adolescent MZ twins report discordant peer relationships and, if so, whether they perceive them as causes, consequences or correlates of discordant behaviour. We gathered free-response questionnaire data from 497 families and conducted in-depth telephone interviews with 97 of them. Within this dataset n = 112 famil...

Previous research suggests that automatic prejudice directly manifests in nonverbal behavior. The authors offer a more complex picture of the relation between automatic processes and nonverbal behavior by suggesting that any discomfort that appears in nonverbal behavior stems not from negative attitudes per se but from discordance between automatically activated attitudes toward Blacks and the ...

QUALIFLEX (QUALItative FLEXible multiple criteria method) is a very useful outranking method to deal simultaneously with the cardinal and ordinal information in decision making process. The purpose of this paper is to develop a hesitant fuzzy QUALIFLEX with a signed distance-based comparison method for handling multi-criteria decision-making problems in which both the assessments of alternative...

In the last article [1], we grouped complex congenital cardiac defects into four subgroups with the rules of cardiac segmental coding [2]. Recently, we found some incongruities presented in these categories, so a newly revised edition (Table 1) to correct the concept is mandatory for the many readers. There are no changes in the group of atrioventricular (AV) and ventricular-arterial (V-A) conc...

A new approach to analyze the p53 mutation database of the European Molecular Biology Laboratory for a comparison of mutation spectra is described, with the aim of investigating organ specificity of etiological factors and putative organ-to-organ relationships in cancer pathogenesis. The number of entries of each nucleotide- and base-pair substitution-specific mutation was divided by the total ...

CONTEXT Little is known about the frequency of discordant diagnoses identified during research. OBJECTIVE To describe diagnostic discordance identified during research and apply a newly designed research framework for investigating discordance. DESIGN Breast biopsy cases (N = 407) from registries in Vermont and New Hampshire were independently reviewed by a breast pathology expert. The foll...

In an effort to investigate the molecular basis of growth discordance in embryos that experience the same uterine environment, we compared telomerase activity and apoptosis in placental trophoblasts obtained from growth discordant twins. Between January 2003 and February 2005, placental tissue from twenty pairs of twins was obtained within thirty minutes of delivery. Eleven cases were classifie...

AIMS The present analysis addresses the potential clinical and physiologic significance of discordance in severity of coronary artery disease between the angiogram and fractional flow reserve (FFR) in a large and unselected patient population. METHODS AND RESULTS Between September 1999 and December 2011, FFR and percent diameter stenosis (DS) as assessed by quantitative coronary angiography w...

Genetic-epidemiological studies on monozygotic (MZ) twins have been used for decades to tease out the relative contributions of genes and the environment to a trait. Phenotypic discordance in MZ twins has traditionally been ascribed to non-shared environmental factors acting after birth, however recent data indicate that this explanation is far too simple. In this paper, we review other reasons...