Stochastic population processes may cause differences between species histories and gene histories. These processes are assumed to only influence the most recent divergences in the tree of life; however, there may be underappreciated potential for microevolutionary processes to impact deep divergences. I used multispecies coalescent models to determine the impact of stochastic processes on deep...

STUDY QUESTION Is there an association between discordance in embryonic growth and fetal loss at the time of the 11-14-week scan in twin pregnancies? SUMMARY ANSWER Regardless of the chorionicity, crown rump length (CRL) discordance at 7(+0)-9(+6) weeks is predictive of subsequent single fetal demise in the first trimester. WHAT IS KNOWN ALREADY Previous small studies have reported a variab...

Objective: We examined the validity of the 20-year-old established Asian norms for pulmonary function in a contemporary cohort of Hong Kong Chinese university students. Design and participants: Pulmonary function testing was conducted in university students (n 805). Setting: A university campus in Hong Kong. Measurements and results: Parameters recorded included gender, age, height, weight, sta...

539 In this issue of Circulation, Samia Mora, Julie Buring, and Paul Ridker publish an elegant and clinically-relevant analysis examining discordance of low-density lipoprotein cholesterol (LDL-C) with related laboratory measures and the risk implications. The article should attract attention from a diverse set of contingents, such as those based in preventive cardiology, clinical lipidology, a...

Diagnostic discordance for osteoporosis is the observation that the T-score of a patient varies between skeletal sites, falling into 2 different diagnostic categories identified by the World Health Organization classification system. Densitometrists and clinicians should expect that at least 4 of every 10 patients tested by dual-energy X-ray absorptiometry (DXA) to demonstrate T-score discordan...

539 In this issue of Circulation, Samia Mora, Julie Buring, and Paul Ridker publish an elegant and clinically-relevant analysis examining discordance of low-density lipoprotein cholesterol (LDL-C) with related laboratory measures and the risk implications. The article should attract attention from a diverse set of contingents, such as those based in preventive cardiology, clinical lipidology, a...

539 In this issue of Circulation, Samia Mora, Julie Buring, and Paul Ridker publish an elegant and clinically-relevant analysis examining discordance of low-density lipoprotein cholesterol (LDL-C) with related laboratory measures and the risk implications. The article should attract attention from a diverse set of contingents, such as those based in preventive cardiology, clinical lipidology, a...

Phylogenomics has ushered in an age of discordance. Analyses often reveal abundant discordances among phylogenies of different parts of genomes, as well as incongruences between species trees obtained using different methods or data partitions. Researchers are often left trying to make sense of such incongruences. Interpretive ways of measuring and visualizing discordance are needed, both among...

OBJECTIVES The feasibility of long-term outcome prediction using BMIPP myocardial scintigraphy was evaluated in cases of acute myocardial infarction. METHODS BMIPP myocardial scintigraphy was performed on 165 patients with first acute myocardial infarction at the time of discharge from the hospital (average of 27 days after disease on set). Discordance between early and delayed image was chec...