The Rat Genome Database (RGD, http://rgd.mcw.edu) was developed to provide a core resource for rat researchers combining genetic, genomic, pathway, phenotype and strain information with a focus on disease. RGD users are provided with access to structured and curated data from the molecular level through to the level of the whole organism, including the variations associated with disease phenoty...

Leptospirosis is an acute infectious disease in humans caused by Leptospira sp. This classified as a zoonosis that usually occurs during the flood and commonly transmitted through rat urine. contact with animals or environment have been contaminated Leptospira. There are wide spectrum clinical manifestations of leptospirosis varying from self-limited to severe disease. enters human body conjunc...

objective: asthma is an airway complex disease defined by reversible airway narrowing and obstruction, chronic airway inflammation, airway hyperresponsiveness, and tissue remodeling. the purpose of this study was to determine the effect of brassica napus l. (b. napus) on airway pathologic changes in a rat model of asthma. materials and methods: twenty-four rats were divided into 4 groups: contr...

The neurodegenerative diseases are characterized by the depletion of neuronal physiology and death as a virtue potential oxidative stress. Parkinson’s disease is one debilitating wherein dopaminergic neurons results mainly in motor dysfunction. present study was focused to neuroprotective effect ethanolic extract Portulaca quadrifida L. (Portulacaceae) against like symptoms. experimental design...

The prognosis of patients with metastatic non-small cell lung cancer depends not only on the general condition and stage disease but also treatment method. Management in 4, usually requires a multidisciplinary approach. Frequently process, we combine local systemic treatment. By detecting new therapeutic targets, can incorporate elements therapy. In described case, sequence: chemotherapy, immun...

1. From a single strain of Wistar rats two lines of normotensive rats (NR) and two lines of hypertensive rats (SHR) were developed by selective breeding. 2. One line of normotensive rats and one of hypertensive rats were used as recipients and the remaining two were used as donors for cross-transplantation of kidneys from hypertensive to normotensive rats and vice versa. Transplantations betwee...

Hypertensive disorders of pregnancy (HDP) contribute to high percentage for both maternal and foetal morbidity mortality associate with long term complications. A history having HDP is a known risk factor women's cardiovascular disease later in their life even though blood pressure normalizes during postpartum period. L-NAME drug that has been used pharmacologically induce hypertension by inhib...