Background and Objective: Anti-inflammatory property of nobiletin (NOB) is proven and neuroinflammation is involved in triggering and progression of neurodegenerative disorder such as Parkinson's disease (PD). PD is a neurodegenerative disorder characterized by motor and non-motor features including psychiatric symptoms such as depression and anxiety. The purpose of this study to investigate wh...

diabetes mellitus is the most common cause of chronic renal disorders and end-stage kidney disease in developed countries. it is the major cause of dialysis and transplantation. failure in renal function causes wide disorders in the body. diabetes results in wide range of alterations in the renal tissue. it is believed that early histological changes in diabetic nephropathy are detectable 2 yea...

Identifying genes underlying common forms of kidney disease in humans has proven difficult, expensive, and time consuming. Quantitative trait loci (QTL) for several complex traits are concordant among mice, rats, and humans, suggesting that genetic findings from these animal models are relevant to human disease. Therefore, we reviewed the literature on genetic studies of kidney disease in rat a...

background: sporadic alzheimer’s disease (sad) is caused by genetic risk factors, aging and oxidative stresses. the herbal extract of rosa canina (r. canina), tanacetum vulgare (t. vulgare) and urtica dioica (u. dioica) has a beneficial role in aging, as an anti-inflammatory and anti-oxidative agent. in this study, the neuroprotective effects of this herbal extract in the rat model of sad was i...

Rat models have been used to investigate physiological and pathophysiological mechanisms for decades. With the availability of the rat genome and other online resources, tools to identify rat models that mimic human disease are an important step in translational research. Despite the large number of papers published each year using rat models, integrating this information remains a problem. Res...

Diabetes Mellitus (DM) is an incurable disease that can be prevented clinically from worsening. This based on classification related to pancreatic damage in total or partial so the impact insulin production. Glucose transporter a protein glucose uptake outside cell into and provides important role body's homeostasis. transporter-2 (GLUT-2) found pancreas, liver, kidney. Parameters used are expr...

The bandwidth-intensive applications on Smart-Mobile-Devices (SMDs) are increasing with SMD's colossal growth. overlapped cellular and non-cellular networks, in hot-spot-places, SMDs capabilities significant reasons for this interfaces-RAT (Radio-Access-Technology) can have complementary link characteristics. end-users avail always-best-connectivity (ABC) their RAT This paper proposes an Integr...

Cataract and retinopathy remain the preventable cause of blindness worldwide, many pharmacological strategies have been proposed for treatment these eye diseases. Animal models play an important role in understanding pathophysiological features disease developing a new therapy. In this study, we investigated development cataract retinal lesion with diabetes using obese type 2 diabetic SDT fatty...