Objective(s):We investigated the relationship between the expression of tumor necrosis factor-inducible gene 6 (TSG-6) with inflammation and integrity of the bladder epithelium in the bladder tissues of patients with bladder pain syndrome/interstitial cystitis (BPS/IC) and the mechanism of action using a rat model of BPS/IC.   Materials and Methods: Expression of TSG-6 and uroplakin III was det...

Background: Community Extraordinary events need to be anticipated by preparing a team respond quickly exceptional circumstances and outbreaks at each health center, it is necessary increase the capacity of special personnel Rapid Action Team (RAT). What preparedness fast-moving prevention control Public Health center. Materials/Methods: Quantitative research with cross-sectional approach was im...

Abstract Rats are invasive pest species that commonly infest low-income urban environments. Their association with humans constitutes a threat of rodent-borne disease transmission. We evaluated the outcome chemical and sanitary intervention on rat sightings in seven settlements New Providence, Bahamas. The consisted rodenticide application, education about environmental sanitation, improvement ...

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that affects regions of the brain that control cognition, memory, language, speech and awareness to one’s physical surroundings. The pathological initiation and progression of AD is highly complex and its prevalence is on the rise. In his study, Alzheimer's disease was induced with single injection of amyloid-β (Aβ) peptides (...

The enzyme 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) is selectively expressed in aldosterone target tissues, conferring aldosterone selectivity for the mineralocorticoid receptor. A diminished activity causes salt-sensitive hypertension. The mechanism of the variable and distinct 11β-hydroxysteroid dehydrogenase type 2 gene (HSD11B2) expression in the cortical collecting duct is poorly...

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that affects regions of the brain that control cognition, memory, language, speech and awareness to one’s physical surroundings. The pathological initiation and progression of AD is highly complex and its prevalence is on the rise. In his study, Alzheimer's disease was induced with single injection of amyloid-β (Aβ) peptides (...

Background Both amyloid beta (Aβ) and tau pathologies co-exist in Alzheimer’s disease. While studies have shown that Aβ interaction results elevated AD pathology, it is not clearly understood how they might affect one another during early pathology stages leading to plaque formation. This study aimed at determining which extent a combination of gradually developing exacerbate each other the con...

Objective: Alzheimer's disease is a neurodegenerative disorder characterized by accumulation of amyloid beta in the hippocampus. In recent decades, herbal medicine has been widely used to treat many neurodegenerative disorders,as in comparison to conventional drugs, herbal remedies exert minimal side effects. Here, the effects of thymoquinone, as the main active component of Nigella sativa, on ...