Bacteriophage M13 major coat protein has been incorporated at different lipid/protein ratios in lipid bilayers consisting of various ratios of dimyristoylphosphatidylcholine (DMPC) to dimyristoylphosphatidylglycerol (DMPG). Spin-label ESR experiments were performed with phospholipids labeled at the C-14 position of the sn-2 chain. For M13 coat protein recombinants with DMPC alone, the relative ...

The ligands of certain G-protein coupled receptors (GPCRs) are membrane soluble and reach their target from the lipid bilayer. Lipid composition and dynamics will therefore modulate the activity of these receptors, but specific roles of lipid components, including the ubiquitous cholesterol (Chol), are not clear. We have probed the organization and dynamics of such a lipid-bilayer-penetrating l...

In this paper, the cooperative distributed model predictive control (DMPC) problem of a class complex systems consisting several subsystems is studied. The states these are coupled with each other, and thus bring challenges for algorithm. Moreover, though can communicate they only access to output information their neighboring subsystems. case, Luenberger observers used estimate unknown predict...

Apolipoprotein (apo) A-II, the second most abundant protein after apo A-I of human plasma high-density lipoproteins (HDL), is the most lipophilic of the exchangeable apolipoproteins. The rate of microsolubilization of dimyristoylphosphatidylcholine (DMPC) membranes by apo A-I to give rHDL increases as the level of membrane free cholesterol (FC) increases up to 20 mol % when the level of reactio...

In this work, we consider output-feedback distributed model predictive control (DMPC) based on state estimation with bounded process disturbances and output measurement noise. Specifically, a scheme observer-enhanced moving horizon (DMHE) is considered for purposes. The DMHE ensures that the estimates of system reach small neighborhood actual values quickly then maintain within neighborhood. Th...

In the article, we study distributed model predictive control (DMPC) problem for a network of linear discrete-time systems, where system dynamics are decoupled, constraints coupled, and communication networks described by time-varying directed graphs. A novel optimization algorithm called push-sum dual gradient (PSDG) is proposed to solve DMPC in fully way. We prove that sequences primal, varia...

We have studied the phase behavior of binary mixtures of long- and short-chain lipids, namely, dimyristoyl phosphatidylcholine (DMPC) and dihexanoyl phosphatidylcholine (DHPC), using optical microscopy and small-angle neutron scattering. Samples with a total lipid content of 25 wt %, corresponding to ratios Q ([DMPC]/[DHPC]) of 5, 3.2, and 2, are found to exhibit an isotropic (I) --> chiral nem...

This note investigates the stabilization problem of a class of spatially decoupled systems by applying distributed model predictive control (DMPC) with switched cost functions. The proposed DMPC scheme switches the optimization index on a switching surface generated by control invariant sets. By applying the index-switching strategy, stability of the closed-loop system is ensured by the feasibi...

In order to investigate structural and dynamical properties of local anesthetic articaine in a model lipid bilayer, a series of molecular dynamics simulations have been performed. Simulations were carried out for neutral and charged (protonated) forms of articaine inserted in fully hydrated dimyristoylphosphatidylcholine (DMPC) lipid bilayer. For comparison purpose, a fully hydrated DMPC bilaye...