Handling & Preparation Instructions This purified fatty acid is liquid at room temperature (oil) and not soluble in water. The product is supplied sterile. It can be solubilized in undiluted serum, ethanol or DMSO. The solubility of Docosahexaenoic acid in ethanol is at least 100 mg/ml. Docosahexaenoic acid has a solubility of 1 mg/ml in a solution of 0.15 M Tris-HCL (pH 8.5). We strongly recom...

Introduction Docosahexaenoic acid (DHA) is an omega-3 fatty acid that falls into the larger category of polyunsaturated fatty acids (PUFAs). Although many chronic conditions are associated with excessive intake of dietary saturated and trans fatty acids (including obesity, insulin resistance, coronary heart disease, and some forms of cancer), research shows omega-3 fatty acids, including DHA, a...

OBJECTIVE We investigated the effect of docosahexaenoic acid (DHA) on the invasion and metastasis of ovarian cancer cells (A2780, HO8910, and SKOV-3). METHODS Cytotoxicity assay was performed to determine the optimal doses of DHA in this experiment. The effects of DHA on invasion ability were assessed by invasion assay. The expressions of messenger RNA and/or proteins associated with invasion...

BACKGROUND There are plausible mechanisms for how dietary docosahexaenoic acid (DHA), an n-3 polyunsaturated fatty acid, could prevent Crohn's disease (CD). AIM To conduct a prospective study to investigate the association between increased intake of DHA and risk of CD. METHODS Overall, 229 702 participants were recruited from nine European centres between 1991 and 1998. At recruitment, die...

objective: type 2 diabetes mellitus (dm-2) is a chronic and progressive metabolic disorder known as a serious threatening condition in the individual and society. type 2 diabetes mellitus is known as the major cause of cardiovascular diseases (cvd). contradictory evidences about the effect of omega-3 fatty acids on cvd risk factors, particularly hypertension. the aim of this study was to determ...

Docosahexaenoic acid (DHA) is important for infant development. The DHA transfer from maternal diet into human milk has not been investigated in detail. We studied the effects of DHA supplementation on the fatty acid composition of human milk and the secretion of dietary (13)C-labeled fatty acids, including DHA, into human milk. Ten lactating women were randomized to consume, from 4 to 6 weeks ...

Background: Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are associated with protection against components of the metabolic syndrome, but the role of a-linolenic acid (ALA), the metabolic precursor of EPA and DHA, has not been studied. The D-desaturase enzyme converts ALA into EPA and DHA, and genetic variation in the D-desaturase gene (FADS2) may affect this