After Alzheimer's disease, Parkinson's disease is the most common nerve-damaging disease. Parkinson's is a progressive and chronic disease where cells secrete dopamine-cut black flesh and in the absence of dopamine in the brain destroyed the irregular body movements. Man eats the food that causes the formation of the neurotransmitters. Tthree neurotransmitters: dopamine, serotonin, norepinephri...

We report the polymerization of dopamine analogue 4-(2-azidoethyl)benzene-1,2-diol (dopamine azide), where amine group is switched to azide, resulting in particles stable water but, contrast other polycatechol based polymers, soluble organic solvents.

previous studies had reported that extracellular levels of ascorbic acid have modulatory effects on dopamine receptors. both ascorbic acid and dopamine receptor have an important role in learning and memory processes. however, the central interaction between ascorbic acid and dopamine d2 receptor on spatial learning and memory has not yet been elucidated. all experiments were carried out on mal...

morphine was used as a remedy for the control of diarrhea centuries before it's sedative-analgesic effect was discovered. although several mechanisms have been proposed for the morphine-induced inhibition of gastrointestinal transit (oit), the exact mechanism has not yet been identified. on this basis the possible involvement of the dopaminergic system in morphine-induced inhibition of tra...

the dopamine has been studied theoretically at the b3lyp/6-31g* level were performed in gasphase. we calculated physical parameters like atomic charges, energy (=>), asymmetry parameter(?), chemical shift @iso, dipole moment and isotropic nmr determinant and in this work we usedgaussian 03 at nmr and calculation by using b3lyp methods with 6-31g* basis set.

Abstract Controlled and targeted drug delivery systems consist of a carrier matrix one or more active ingredients. One the roles is to regulate release drug. Uptake, release, differential scanning microcalorimetry (DSC) powder X-ray diffraction (XRD) techniques were used reveal interactions governing dopamine indole from thermoresponsive model polymer gel. The can be completely recovered loaded...

The regulation of dopamine and serotonin synthesis in rat brain striatal synaptosomes has been studied using HPLC methods. Noradrenaline was shown to markedly inhibit both the synthesis of dopamine and serotonin. The response of the synaptosomes to the concentrations of noradrenaline appeared to be biphasic, a very effective inhibition occurring at low concentrations (1-5 µm) and a relativ...