Background: Traumatic brain injury is one of the most important causes of death in trauma patients among the different types of trauma worldwide. In this study, the effect of curcumin on the outcome of severe traumatic brain injury,. Methods: This was a double-blind and paralleled randomized controlled study that was conducted on 128 patients aged 18 to 70 with severe brain trauma. Patients we...

objective: to determine the prediction value of disorder of consciousness scale (docs) for consciousness recovery after traumatic brain injury (tbi) leading to coma. methods: this is a descriptive-cross-sectional study of the correlation between the level of patients’ consciousness in the first and second weeks and the first 2 months after traumatic brain injury, using docs scale. results: the ...

The relationships between spatial attention and conscious perception are currently the object of intense debate. Recent evidence of double dissociations between attention and consciousness cast doubt on the time-honored concept of attention as a gateway to consciousness. Here we review evidence from behavioral, neurophysiologic, neuropsychological, and neuroimaging experiments, showing that dis...

Post-concussion syndrome has presented clinicians with controversy and intrigue for at least 130 years. Its symptoms, which often follow uncomplicated mild head injury (post-traumatic amnesia 51 h, Glasgow Coma Scale score 13–15, loss of consciousness 515 min) and moderate head injury (post-traumatic amnesia 1–24 h, Glasgow Coma Scale score 9–12, loss of consciousness 15 min to 6 h), commonly i...

A multicenter double-blind placebo-controlled study of cytidine 5'-diphosphocholine (CDP-choline) was conducted to evaluate possible clinical benefits of the drug in patients with acute, moderate to severe cerebral infarction. The patients included also suffered from moderate to mild disturbances of consciousness, and all were admitted within 14 days of the ictus. Patients were allocated random...

This study was aimed to identify impaired attentional components in mild CHI patients. The CHI features taken into account were age (< or = 30 vs. > 30 years), loss of consciousness (yes vs. no), and time after injury (few days vs. some months). The groups tested were composed of 26 patients and 26 controls (matched for age, sex and education). Experiment 1 used a dual-task paradigm (Umiltà et ...