Background: Liver cancer is the second outstanding reason for cancer-related death global and thus a main public health challenge. Plant-based drugs are regarded as promising therapies. Basil and Dracocephalum kotschyi extracts have shown therapeutic impacts on various cancers. Therefore, we assessed the effects of the extract of Basil and Dracocephalum kotschyi on cell proliferation and BCL2 e...

Dracocephlum kotschyi Boiss is a genus in Lamiaceae family and medicinal herb native to Iran. The cell suspension cultures were treated by static magnetic field (SMF) Fe3O4 magnetite nanoparticles (MNP) understand the production yield of secondary metabolites. treatment procedure was done cultivating cells either with 100 ppm MNP, SMFs, or simultaneous exposure both MNP SMFs. SMF at 30 mT unifo...

Background: Breast cancer is the most prevalent malignancy among women in the worldwide and the outbreak in Iranian women is growing. Iranian patients with breast cancer are younger than their Western counterparts. Dracocephalum kotschyi is a wild-growing flowering plant belonging to the family Labiatae and found in Iran. This plant has been applied in Iran folk medicine. The aim of this study ...

Background and objectives: Tuberculosis (TB) is the major public health problem in the world. Each year there are 2-3 million deaths worldwide caused by TB. The increasing incidence of Multi Drug Resistance tuberculosis (MDR-TB) worldwide highlights the urgent need to search for new antituberculosis compounds. It has been reported that medicinal plant, Dracocephalum kotschyi, possesses some ant...

Dracocephalum kotschyi is an essential oil containing plant found in Iran. In Iranian traditional medicine, D. kotschyi has been used as antispasmodic and analgesic but so far there is no pharmacological report about its antispasmodic activity. Therefore, the objective of this research was to study antispasmodic activity of the essential oil of D. kotschyi and two of its constituents namely lim...

dracocephalum kotschyi boiss, a member of labiatae family, is a native plant to iran, which has been reported to have immunomodulatory, antihyperlipidemic and antispasmodic activities. the objective of this research was to study the antispasmodic and antidiarrhoeal activities of hydroalcoholic and hexane extracts of d. kotschyi in mice. furthermore, the antidiarrhoeal and antispasmodic effect o...

dracocephalum kotschyi boiss. (labiatae) is a traditional medicine which is believed to have antispasmodic and analgesic activities. the antispasmodic action of d. kotschyi essential oil has been shown in a previous report. the objective of this research was to study antispasmodic activity of hydroalcoholic extract of d. kotschyi on ileum contractions. hydroalcoholic extract was obtained from a...