nowadays, developements in nanotechnology have leeds an increased application of this newborn technology in cancer treatment. in this study, a stabilized micelle was developed to load hpd in order to be used in photodynamic treatment of cancer in an animal model. to construct micelles, pluronic p-105 was used and stabilized to encapsulate hpd . this process includes a 24 h polymerization in whi...

hydrogels are introduced to modem medicine as novel materials suitable for a variety ofbiomedical applications. studying hydrogels as novel biomaterials has become a fast-developingand exciting research field during the last two decades. these interesting biomaterials have found awide range of application including contact lenses, vehicles for drug delivery and scaffold in tissueengineering and...

curcumin is a hydrophobic polyphenol and major bioactive component of turmeric with known anti-inflammatory, neurogenesis, antioxidant, and anti-carcinogenic effect. curcumin antagonizes many steps in the inflammatory cascade, including inhibition of nf-κb (nuclear factor kappa-light-chain-enhancer of activated b cells), activator protein-1 transcription and inos (induced nitric oxide synthases...

ethosomes are a novel and alternative drug delivery systems and currently the focus of many research activities. ethosomes are soft, flexible vesicles that are composed mainly of phospholipids, ethanol and water. ethosomes can provide better skin permeation than liposomes and deliver enhanced amounts of both small and large therapeutic agents through skin and targeting to deeper skin layers for...

objective(s): nanoparticles (nps) are known for their specific accumulation in the inflamed tissues of the colon and thus allow a selective delivery to the site of inflammation with minimum adverse effects. the main objective of this work is to attain mesalamine loaded chitosan nanoparticles as a carrier for oral delivery. methods: in this study, mesalamine loaded chitosan nanoparticles were pr...

this review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (omvs), originating from the surface of gram negative bacteria including their outer membrane proteins and lipopolysaccharides. moreover, the functional roles and applications of omvs in medical research such as omv-based vaccines, omv adjuvants properties, omv ...

intravitreal injection is the most common approach for drug delivery to the posterior segment in humans. however, following the injection, drugs are rapidly eliminated from the vitreous, with half-lives up to a few days. depending on the rate of clearance from the vitreous, large boluses and frequent administrations may be required to ensure therapeutic levels over an extended period of time. m...

objective(s): in this research, zeolite x and zeolite y were used as vehicle to prepare intestine targeted oral delivery systems of indomethacin and ibuprofen. materials and methods: a soaking procedure was implemented to encapsulate indomethacin or ibuprofen within synthetic zeolites. gravimetric methods and ir spectra of prepared formulations were used to assess drug loading efficiencies into...

nowadays apphcanon of nanotubes in biology and medicinal science is more investigated. nanotubes can passthroueh cell walls and transport and release drugs in special tissues. the purpose of this paper is to investigatethe interaction of a nanotube having hydroxyl functional groups (oh) with an anticancer agent. in this worktransporting of an anticancer drug named 2-(2-amino 6,7-dimethyl pterid...

carvacrol is one of the main components of the eo of some labiatae (laminaceae) members like oregano, thyme and savory. carvacrol has a lot of health benefits for example, antibacterial, and antioxidant activity.we synthesized some silicon derivatives of carvacrol, and characterized them by standard methods. then the monomer of dimethylvinylsilyl carvacrol was synthesized. copolymer of this mon...