Pharmacokinetics of ceftriaxone was studied in buffalo calves (Bubalus bubalis) after single intravenousand intramuscular administration of 10 mg/kg body weight. The drug concentrations in plasma samples weremeasured by high performance liquid chromatography with UV detection. Following intravenousadministration, the drug was rapidly distributed (Cpo: 106.5 ± 9.64 μg/ml; t1/2α: 0.09 ± 0.01 h; V...

AIMS To identify factors associated with time to initiation of (i) sex work prior to injecting drugs initiation; (ii) injection drug use prior to sex work initiation; and (iii) concurrent sex work and injection drug use (i.e. initiated at the same age) among female sex workers who currently inject drugs (FSW-IDU). DESIGN Parametric survival analysis of baseline data for time to initiation eve...

For almost all injecting drug users (IDUs), the first site of injection is the arm. Years after injection, IDUs may shift to using other sites for intravenous (IV) access. Although injection to sites other than the arm is associated with higher risks, literature is limited regarding this behavior. We aimed to determine the prevalence and associated factors of using IV access points other than t...

Drug Free Tumor Theranostics In article number 2205165, Tymish Y. Ohulchanskyy and co-authors introduce hemoglobin nanocrystals for drug free, synergistic selective theranostics of colon cancer. After intravenous (i.v.) injection, these target tumor react with tumor-specific H2S H2O to enable magnetic resonance imaging guided photothermal therapy produce •OH chemodynamic therapy.