objective(s):   the ongoing increasing antibiotic resistance is one of the biggest challenges faced by global public health. the perennial need for new antimicrobials against a background of increasing antibiotic resistance in pathogenic and opportunistic microorganisms obliges the scientific community to constantly develop new drugs and antimicrobial agents. lichens are known prolific sources ...

conclusions although previous studies have shown that a-g transition mutations in 23 srrna gene (domain v) are the main reason for the occurrence of high level macrolides resistance in b. pertussis, however, the mentioned single nucleotide polymorphisms (snps) have not been detected in our resistant strain. this is the first report of high level macrolide resistant b. pertussis, without snps in...

background: in order to deworm the ruminants especially of sheep in iran, consumption of benzimi­dazoles has more than 2 decades history and today farmers are using imidazothiazoles, macrocyclic lactones and mostly benzimidazole compounds (bzs) to treat infected farm animals. it has been demonstrated that the most common molecular mechanism leading to bzsresistance in haemonchus contortus is a ...

conclusions antibiotic resistance gene cassettes may be carried on integron or other genetic elements. the purpose of this study was to detect integron or genomic islands involved in antibiotic resistance profile of the isolates of h. influenzae collected in this study. results of the twenty isolates, all (100%) were resistant to clindamycin, chloramphenicol and tetracycline, 95% to amoxicillin...

results no significant correlation was seen in rs3743527 and rs129081 polymorphism’s allelic and genotypic frequencies between the patient group and control individuals (p value > 0.05). the average frequencies of rs129081 g and c alleles was 40 (58%) and 29 (42%), respectively. in our sample the average frequencies of rs3743527 c and t alleles, were 41 (61%) and 28 (39%), respectively. the res...

conclusions: this study detected multiple drug resistance in pseudomonas aeruginosa including resistance to β-lactams, aminoglycosides, and fluoroquinolones. therefore, identification of drug resistance patterns in p. aeruginosa and detection of pan-resistant producing isolates are of great importance in prevention and control of infections in burn center ward. background: serious infections by...

background and objectives: non-fementer gram-negative bacilli (nfgb) are ubiquitous pathogen that has emerged as a major cause of health care associated infections. the aim of this study was to determine the prevalence and antimicrobial susceptibility of   nfgb in an iranian hospital. materials and methods: fromjuly 2005 to november 2006 a total of 257 strains of nfgb including 109 (42.41%) str...

in this report, β-tubulin gene polymorphism was investigated in haemonchus contortus  populations isolated from sheep flocks in different regions of khouzestan province, southwestern iran. the samples were chosen on the basis of regional variation in benzimidazole treatment background of sheep flocks. our objective was to study the relationship between treatment background andβ -tubulin gene po...