Under acute or chronic stresses, the adult heart undergoes a remodeling process that involves cardiomyocyte hypertrophy accompanied by apoptosis, necrosis, and fibrosis that lead to impaired cardiac contractility. The role of endogenous regeneration in this process is currently under investigation. Sustained deleterious stimuli will lead to a decompensated form of hypertrophy often culminating ...

Cilia are hair-like cellular protrusions important in many aspects of eukaryotic biology. For instance, motile cilia enable fluid movement over epithelial surfaces, while primary (sensory) cilia play roles in cellular signalling. The molecular events underlying cilia dynamics, and particularly their disassembly, are not well understood. Phosphatase and tensin homologue (PTEN) is an extensively ...

conclusions the tmd, with a cut-off point of 65 mm, had superior diagnostic value compared with the hmdr and mallampati score. therefore, the tmd could be used in malay patients to predict the difficulty of larynx visualization during laryngoscopy. results difficulty in visualizing the larynx was found in 28 (10.1%) patients. the auc, sensitivity, and specificity for the three airway predictors...

Wnt/Frizzled (Fz) signaling controls cell polarity/movements during vertebrate gastrulation via incompletely defined mechanisms. We demonstrated previously that Wnt/Fz activation of Rho, a GTPase and regulator of cytoskeletal architecture, is essential for vertebrate gastrulation. Here we report that in mammalian cells and Xenopus embryos, Wnt/Fz signaling coactivates Rho and Rac, another GTPas...

In this work, three complexes were synthesized from the trivalent europium ion (EuIII), using picrate anion (pic), and delta-valerolactam (DVL), epsilon-caprolactam (EPK), oenantholactam (OEN). The [Eu(pic)3∙(DVL)3], [Eu(pic)3∙(EPK)3], [Eu(pic)3∙(OEN)3] studied as luminescent markers for application security elements in Brazilian banknotes. All showed red color emission with absorption at 397 n...

Autonomous underwater vehicles (AUV) perform various applications such as seafloor mapping and structure health monitoring. Commonly, an inertial navigation system aided by a Doppler velocity log (DVL) is used to provide the vehicle’s solution. In fusion, DVL provides vector of AUV, which determines solution’s accuracy helps estimate states. This paper proposes BeamsNet, end-to-end deep learnin...

Multiple signaling pathways, including Wnt signaling, participate in animal development, stem cell biology, and human cancer. Although many components of the Wnt pathway have been identified, unresolved questions remain as to the mechanism by which Wnt binding to its receptors Frizzled and Low-density lipoprotein receptor-related protein 6 (LRP6) triggers downstream signaling events. With live ...

This paper represents a first step towards a navigation system based on a ARGONAUT DVL (Doppler Velocity Log) sensor for an underwater remotely operated vehicle (ROV). The sensor measures the water currents, the vehicle ground speed, the altitude, the depth and its attitude. The navigation system is formulated in a way that is able to deal with the future integration of new sensors like a DGPS....