There is increasing evidence that intermittent hypoxia resulting from obstructive sleep apnoea (OSA) is independently associated with dyslipidaemia. Currently, no data exist on potential links between OSA-related dyslipidaemia and susceptibility genes for dyslipidaemia in such patients. Our aim was to study the effects of the apolipoprotein E (APOE) genotype and sleep apnoea severity on atherog...

Piper sarmentosum (PS) is a traditional medicinal herb used by South East Asians. It demonstrates promising properties against various non-communicable diseases and infectious agents due to its antioxidant anti-inflammatory properties. Given that oxidative stress inflammation are involved in developing exacerbating metabolic syndrome (MetS) principal components (central obesity, hyperglycaemia,...

D yslipidaemia, characterised by elevated total cholesterol, elevated non–high density lipoprotein (HDL) cholesterol, low HDL cholesterol, and elevated triglycerides, is common in patients with HIV who are treated with long-term antiretroviral therapy (ART) [1]. Although multiple factors infl uence lipid levels in patients treated with ART, exposure to protease inhibitors (PI) is thought to pla...

Introduction Treatment of dyslipidaemia complicated by chronic kidney disease is important for preventing the development of cardiovascular disease. The pathogenesis of dyslipidaemia associated with chronic kidney disease varies depending on urinary protein level and the stage of chronic kidney disease. Hypocholesterolaemia is associated with malnutrition and inflammation and also leads to the ...

Stroke is an abrupt onset of a neurological deficit that is attributable to a focal vascular cause. It is encountered quite frequently in clinical practice. The role of circulating lipids and lipoproteins in the pathogenesis of young stroke remains uncertain even after decades of research. Diabetes is an important cause for dyslipidaemia. In this present study an attempt is made to evaluate the...

The European Society of Cardiology together with the European Atherosclerosis Society published updated dyslipidaemia guidelines in 2011. SA Heart and the Lipid and Atherosclerosis Society of Southern Africa officially adopt these guidelines. This statement adapts aspects of the guidelines to the South African situation. Using the updated Framingham risk charts, interventional strategies are ba...

On the basis of a high correlation, non-HDL-C (non-high-density lipoprotein cholesterol) and apoB (apolipoprotein B) have been suggested to be of equivalent value for clinical practice; however, the strength of this relationship has not been examined in detail in patients with dyslipidaemia. The present study examines the variance of non-HDL-C compared with apoB in 1771 consecutive patients eva...

BACKGROUND Despite evidence of the benefits of prevention activities, studies have reported only partial integration and great variability of screening in daily clinical practice. The study objectives were: 1) To describe Primary Health Care (PHC) screening for arterial hypertension, dyslipidaemia, obesity, tobacco use, and excessive alcohol consumption in 2008 in 2 regions of Spain, based on e...


 Background. In South Africa, the prevalence of dyslipidaemia and hypertension (HT) in paediatric diabetes patients is unknown. Objectives. To determine HT diabetic seen at Tygerberg Hospital (TBH) establish whether either associated with body mass index (BMI), glycosylated haemoglobin (HbA1c) or duration diabetes. Further, to differs between two specified periods.Methods. A retrospective...