A serosurvey of anti-Ebola Zaire virus nucleoprotein IgG prevalence was carried out among Ebola virus disease survivors and their Community Contacts in Bombali District, Sierra Leone. Our data suggest that the specie of Ebola virus (Zaire) responsible of the 2013-2016 epidemic in West Africa may cause mild or asymptomatic infection in a proportion of cases, possibly due to an efficient immune r...

On March 20, 2015, a case of Ebola virus disease was identified in Liberia that most likely was transmitted through sexual contact. We assessed the efficiency of detecting Ebola virus in semen samples by molecular diagnostics and the stability of Ebola virus in ex vivo semen under simulated tropical conditions.

dear editor-in-chief the present global consideration is on the recent outbreak of 2014 western ebola virus in west africa (1 – 3). this viral hemorrhagic fever wide spreads to several countries in west africa and remote countries (1 - 3). with high death rate, the disease is presently on the list of public health threatens. the main problem for management of the infection is the limited knowl...

Introduction: Ebola is a viral infection with a high mortality risk and health workers are considered as an at-risk group. The main aim of this study was to determine the knowledge and attitude of health workers about Ebola virus disease (EVD) in Yazd city, Iran. Methods: This cross-sectional study was carried out on 110 health workers in health centres of Yazd city, Iran in 2015, who were sel...

BACKGROUND Clinical management of Ebola virus disease remains challenging. Routine laboratory analytics are often unavailable in the outbreak setting, and few data exist for the associated haematological and biochemical abnormalities. We aimed to assess laboratory and clinical data from patients with Ebola virus disease to better inform clinical management algorithms, improve understanding of k...

BACKGROUND The ongoing Ebola outbreak in West Africa has resulted in 28 646 suspected, probable, and confirmed Ebola virus infections. Nevertheless, malaria remains a large public health burden in the region affected by the outbreak. A joint Centers for Disease Control and Prevention/National Institutes of Health diagnostic laboratory was established in Monrovia, Liberia, in August 2014, to pro...

Ebola hemorrhagic fever is a severe, usually fatal illness caused by Ebola virus, a member of the filovirus family. The use of nonhomologous immune serum in animal studies and blood from survivors in two anecdotal reports of Ebola hemorrhagic fever in humans has shown promise, but the efficacy of these treatments has not been demonstrated definitively. We have evaluated the protective efficacy ...

www.thelancet.com/infection Vol 15 February 2015 141 4 Lipsitch M, Cohen T, Cooper B, et al. Transmission dynamics and control of severe acute respiratory syndrome. Science 2003; 300: 1966–70. 5 Fraser C, Donnelly CA, Cauchemez S, et al. Pandemic potential of a strain of infl uenza A (H1N1): early fi ndings. Science 2009; 324: 1557–61. 6 Lewnard JA, Ndeff o Mbah ML, Alfaro-Murillo JA, et al. Dy...

Little is known about potentially modifiable factors in Ebola virus disease in children. We undertook a retrospective cohort study of children <13 years old admitted to 11 Ebola holding units in the Western Area, Sierra Leone, during 2014-2015 to identify factors affecting outcome. Primary outcome was death or discharge after transfer to Ebola treatment centers. All 309 Ebola virus-positive chi...

BACKGROUND Ebola virus disease is a highly virulent and transmissible disease. The largest recorded fatality from Ebola virus disease epidemic is ongoing in a few countries in West Africa, and this poses a health risk to the entire population of the world because arresting the transmission has been challenging. Vaccination is considered a key intervention that is capable of arresting further sp...