Objective. To investigate the safety (risk) and efficacy (benefit) of Echinacea purpurea extract in the prevention of common cold episodes in a large population over a 4-month period. Methods. 755 healthy subjects were allocated to receive either an alcohol extract from freshly harvested E. purpurea (95% herba and 5% root) or placebo. Participants were required to record adverse events and to r...

BACKGROUND Echinacea sales represent 10% of the dietary supplement market in the United States, but there is no guarantee as to the content, quality, variability, or contamination in Echinacea preparations. OBJECTIVE To qualitatively and quantitatively assess the contents of Echinacea-only preparations available in a retail setting. METHODS One of each single-herb Echinacea preparations tha...

Low and erratic seed germination presents a major production problem in the medicinal plants that collectively are called echinacea or purple coneflower (Echinacea angustifolia and E. pallida). In this study, nine seed lots of each E. pallida and E. angustifolia from a wide variety of commercial sources and germplasm collections were collected and treated with a solution of 1.0 mM [144.5 mg·L-1...

The objective of this study was to examine and demonstrate how harvesting age (flower age) contribute to the variations in the quality of Echinacea purpurea (L.) Moench. The effects of different flower developmental stages on caffeic acid derivatives and isobutylamide content are described. These phytochemicals were extracted from fresh plants with 60% ethanol and quantified by the HPLC analysi...

Depending on how this Asteraceae family member is classified, there are up to 12 different species of Echinacea. The most commonly used species for medicinal purposes is Echinacea purpurea, which is easy to cultivate and therefore, product demand does not put a stress on native populations of Echinacea species that are difficult to cultivate. Most preparations found in the market are derived fr...

The introduction of plants is an important task modern botanical science. Relevance significantly increased when introduced species are multifunctional in use. According to our research, these criteria met by representatives the genus Echinacea (Echinacea Moench.), which for most part, previously positioned only as medicinal plants.

BACKGROUND Echinacea preparations are widely used to treat the common cold. OBJECTIVE To assess the efficacy of dried, encapsulated, whole-plant echinacea as early treatment for the common cold. DESIGN Randomized, double-blind, placebo-controlled community-based trial. SETTING University of Wisconsin-Madison, Madison, Wisconsin. PARTICIPANTS 148 registered students with common colds of ...

Aim: This study aims to investigate the possible effects of aqueous Echinacea (E. Purpurea, whole plant) extract on Adenosine deaminase (ADA) activity in cancerous and non-cancerous human gastric and colon tissues. Materials and Methods: Thirty three cancerous and 33 non-cancerous human gastric tissues, and 25 cancerous and non-cancerous human colon tissues removed by surgical operations were s...

INTRODUCTION Respiratory tract infections are common, and these infections occur frequently in children, susceptible adults, and older persons. The risk for recurrences and complications relates not only to the presence of viruses but also to immune function. Therefore, modulation of the immune system and antiviral interventions such as echinacea might reduce the risk of recurrences and possibl...

OBJECTIVE The aim of this study was to determine whether Echinacea purpurea given to children for the treatment of acute upper respiratory tract infection (URI) was effective in reducing the risk of subsequent URI. DESIGN This was a secondary analysis of data from a randomized, double-blind, placebo-controlled trial of Echinacea for the treatment of URI in children. SETTING The study was co...