BACKGROUND To assess the protocols of epidural analgesia versus systemic opioid-based analgesia retrospectively in 1555 thoracotomies in our thoracic centre during 2011-2013. METHODS Pain therapy is aggressive and standardized in our thoracic centre thoughout the complete postoperative stay. Patients receive either standardized epidural analgesia with ropivacaine + sufentanil 4-8 mls/h (500 m...

The aim of this document is to outline the historical development, roles and responsibilities European Defence Agency (EDA), decision-making procedures discuss its activities that could support Lithuanian defence industry. findings show continues play an important role in coordinating participating member states (pMS) their industries, enabling projects, suggesting prioritization tools, fosteri...

Abstract Most conventional statistical methods aiming at defining geochemical concentration thresholds for separating anomalies from background have limited effectiveness in areas with complex geological settings and variable lithology. In this paper, median+2MAD as a method of exploratory data analysis (EDA) and concentration-area (C-A) fractal model as two effective approaches in separation g...

Engineering design and analysis (EDA) software circuit simulators has traditionally focussed virtually exclusively on the scientific calculations performed by the software. Software technology, however, has matured to the point where it can provide significant improvements in the ability of EDA software to address the full requirement of the engineering design flow. In this paper we describe so...

Abstract Objectives Extreme/“pathological” demand avoidance (PDA) describes a presentation found in some children on the autism spectrum, characterized by obsessive resistance to everyday demands and requests. Demands often trigger behavior (e.g., distraction, excuses, withdrawal into role play). Pressure comply can lead escalation emotional reactivity that challenges. Methods Previously, Extre...

Boolean Satisjiability (SAT) is often used as the underlying model for a signijicant and increasing number of applications in Electronic Design Automation (EDA) as well as in many other jields of Computer Science and Engineering. In recent years, new and efJicient algorithms for SAT have been developed, allowing much larger problem instances to be solved. SAT " packages " are currently expected...

Doxorubicin (DOX) is a potent antitumor agent, but the cardiotoxicity mediated by the formation of reactive oxygen species limit its clinical use. The present study aims to explore electrocardiographic and biochemical evidence for the cardioprotective effect of two antioxidants, Lycium barbarum polysaccharides (LBP, the main antioxidant in Lycium barbarum) and edaravone (a potent free radical s...

Two well-known antioxidative nutrients, vitamin E and selenium, were used in this study to investigate possible inhibitory action against the formation of esophageal adenocarcinoma (EAC) in rats. In this model, carcinogenesis is believed to be driven by oxidative stress. Male Sprague-Dawley rats (8 weeks old) were divided into four groups and received esophagoduodenal anastomosis (EDA) surgery ...

To maintain body temperature, sweat glands develop from embryonic ectoderm by a poorly defined mechanism. We demonstrate a temporal cascade of regulation during mouse sweat gland formation. Sweat gland induction failed completely when canonical Wnt signaling was blocked in skin epithelium, and was accompanied by sharp downregulation of downstreamWnt, Eda and Shh pathway genes. The Wnt antagonis...