This study aimed to identify the disease-causing mutation in the ectodysplasin A (EDA) gene in a Chinese family affected by X-linked hypohidrotic ectodermal dysplasia (XLHED). A family clinically diagnosed with XLHED was investigated. For mutation analysis, the coding region of EDA of 2 patients and 7 unaffected members of the family was sequenced. The detected mutation in EDA was investigated ...

Edaravone (EDA) is clinically used for treatment of acute ischemic stroke in Japan and China due to its potent free radical-scavenging effect. However, it has yet to be determined whether EDA can attenuate iodoacetic acid- (IAA-) induced neuronal death in vitro. In the present study, we investigated the effect of EDA on damage of IAA-induced primary cerebellar granule neurons (CGNs) and its pos...

This chapter proposes a combination of estimation of distribution algorithm (EDA) and the 2-opt local search algorithm (EDA/LS) for the quadratic assignment problem (QAP). In EDA/LS, a new operator, called guided mutation, is employed for generating new solutions. This operator uses both global statistical information collected from the previous search and the location information of solutions ...

This committee was appointed by the SPR Board to provide recommendations for publishing data on electrodermal activity (EDA). They are intended to be a stand-alone source for newcomers and experienced users. A short outline of principles for electrodermal measurement is given, and recommendations from an earlier report (Fowles et al., ) are incorporated. Three fundamental techniques of EDA reco...

In broad terms, Exploratory Data Analysis (EDA) can be defined as the numerical and graphical examination of data characteristics and relationships before formal, rigorous statistical analyses are applied. Although the temptation to omit EDA in favor of delving into ANOVAs, MANOVAs and the like is great, the role of EDA cannot be underemphasized. EDA rewards the user with a better understanding...

Design automation of electronic systems [electronic design automation (EDA)] is the engineering science that derives software and hardware tools for the design of integrated circuits and systems based on abstraction, design methodologies, and software implementations of sophisticated algorithms for verification and synthesis. What makes EDA unique is the continuous interplay between theory and ...

The simple diamine diaminoethane (ethylenediamine, EDA) has been shown to activate GABA receptors in the central and peripheral nervous systems, partly by a direct action and partly by releasing endogenous GABA. These effects have been shown to be produced by the complexation of EDA with bicarbonate to form a carbamate. The present work has compared EDA, GABA and β-alanine responses in rat CA1 ...

Today’s Integrated Circuit (IC) architects depend on Electronic Design Automation (EDA) software to conquer the overwhelming complexity of Very Large Scale Integrated (VLSI) designs. As the complexity of IC chips is still fast increasing, it is critical to maintain the momentum towards growing productivity of EDA tools. On the other hand, singlecore Central Processing Unit (CPU) performance is ...

BACKGROUND Epidural analgesia (EDA) is used widely for postoperative pain treatment. However, studies have reported a failure rate of EDA of up to 30%. We aimed to evaluate the quality of postoperative EDA in patients undergoing a laparotomy in five Norwegian hospitals. METHODS This was a multicenter observational study in patients undergoing a laparotomy with epidural-based postoperative ana...

OBJECTIVE Thoracic aortic aneurysm is a common complication in patients with bicuspid aortic valve (BAV). Alternatively spliced extra domain A (EDA) of fibronectin (FN) has an essential role in tissue repair. Here we analyze the expression of FN spliceforms in dilated and nondilated ascending aorta of tricuspid aortic valve (TAV) and BAV patients. METHODS AND RESULTS The mRNA expression was a...