Objective: This study aimed to evaluate the Edinburgh Depression Scale (EDS) as a screening tool for use in a Parkinson’s disease (PD) population. Many commonly-used depression scales include items relating to somatic symptoms that also occur in PD which could potentially result in inaccurate reporting of depressive symptoms. The EDS is a scale which incorporates no somatic items. Method: 120 p...

We present a new computational approach for constant pH simulations in explicit solvent based on the combination of the enveloping distribution sampling (EDS) and Hamiltonian replica exchange (HREX) methods. Unlike constant pH methods based on variable and continuous charge models, our method is based on discrete protonation states. EDS generates a hybrid Hamiltonian of different protonation st...

BACKGROUND The Netherlands has a well-developed primary care system, which increasingly collaborates with hospital emergency departments (EDs). In this setting, insight into crowding in EDs is limited. This study explored links between patients' ED Length of Stay (LOS) and their care pathways. METHODS Observational multicenter study of 7000 ED patient records from 1 February 2013. Seven EDs s...

Leydig cells undergo apoptosis in response to the cytotoxin ethane dimethanesulfonate (EDS), with numbers declining at 12-18 h and maximal apoptosis at 24 h postinjection. The Bcl-2 family members, Bcl-2, Bcl-xl, and Bax, appear not to be involved in this process. To further investigate this phenomena, a single dose of EDS was administered to adult rats to induce the killing of Leydig cells. Th...

physical design of the emergency department (ed) has an important effect on its role and function. to date, no guidelines have been introduced to set the standards for the construction of eds in iran. in this study we aim to devise an easy-to-use tool based on the available literature and expert opinion for the quick and effective assessment of eds in regards to their physical design. for this ...

BACKGROUND A long length of stay (LOS) in the emergency department (ED) associated with overcrowding has been found to adversely affect the quality of ED care. The objective of this study is to determine whether patients who speak a language other than English at home have a longer LOS in EDs compared to those whose speak only English at home. METHODS A secondary data analysis of a Queensland...

Freestanding emergency departments (EDs), which offer emergency medical care at sites separate from hospitals, are a rapidly growing alternative to traditional hospital-based EDs. We evaluated state regulations of freestanding EDs and describe their effect on the EDs' location, staffing, and services. As of December 2015, thirty-two states collectively had 400 freestanding EDs. Twenty-one state...

Excessive daytime sleepiness (EDS) is a frequent symptom of patients with obstructive sleep apnoea (OSA). EDS is a high-risk factor for accidents at work and on the road. Thirty untreated patients with different levels of severity of OSA were studied concerning night sleep and EDS. The criterion for severity was the respiratory disturbance index (RDI): 15 patients were classified as 'moderately...

books in the series :psle, eds., Perspectives on Positive Political Economy tomic Analysis of Property Rights °acle of theMarket: The Political Economy I Development in Kenya ecret: The Cabinet and the Development of nies in Victorian England Strategy: A Century of Swedish Politics ~nglish Edition) 'ontracting for Property Rights :lTerry Sullivan, eds., Congress: Structure and Policy ions, Inst...