Background and Objectives New Delhi metallo-ß-lactamase (NDM) is a newly emerging metallo-ß-lactamases, which can destroy all β-lactams including carbapenems. Therefore, this study aimed at evaluating New Delhi metallo-ß-lactamase-1-production in clinical isolates of Klebsiella pneumoniae in Kashan, Iran. Materials and Methods In a cross-sectional study, 181 K. pneumoniae isolates were collec...

Tooth and bone specimen require extensive demineralization for careful analysis of cell morphology, as well as gene and protein expression levels. The LacZ gene, which encodes the ß-galactosidase enzyme, is often used as a reporter gene to study gene-structure function, tissue-specific expression by a promoter, cell lineage and fate. This reporter gene is particularly useful for analyzing the s...

ß-Lactams are the most widely used antibiotics, and ß-lactamases are the greatest source of resistance to them. Colorimetric tests are good, rapid, indicators of ß-lactamase production and its contingent resistance in Haemophilus, Moraxella and Neisseria spp. They can also be applied to Gram-negative bacilli but are less useful, since the usual question is not whether a ß-lactamase is produced ...

in this study, the chemical factors effect of metal ions, surfactant, oxidizing agents and enzyme inhibitors on the activity of trypsin and chymotrypsin of rainbow trout fry were considered. the results showed that k+ and na+ had not significant decrease on trypsin and chymotrypsin activity than did those from control (p>0.05). ca2+ and mg2+ showed a significant increase in activity of trypsin ...

We evaluated the inducibility of nitrate-dependent Fe(II)-EDTA oxidation (NDFO) in non-growth, chloramphenicol-amended, resting-cell suspensions of Dechloromonas sp. strain UWNR4 and Acidovorax sp. strain 2AN. Cells previously incubated with Fe(II)-EDTA oxidized ca. 6-fold more Fe(II)-EDTA than cells previously incubated with Fe(III)-EDTA. This is the first report of induction of NDFO by Fe(II).

The aim of the present study is to investigate the influence of the environmental factors, smoking and alcohol, on the biotransformation of cyclophosphamide (CP) in the rat in vivo and in vitro with S9 liver fractions. The biotransformation of CP was studied by the determination of the CP metabolites, nor-nitrogen mustard (NNM), 4-ketocyclophosphamide (KCP), and carboxyphosphamide (CAR). The ef...

This cross-sectional study aimed to assess perceptions of healthy food and motivation for health behaviour (MHB) in different Mediterranean countries. Multiple linear regression was used identify the association between perception MHB The highest observed Portugal (median 38.0; IQR 7.0) lowest Greece 34.0; 8.0). Compared Portuguese respondents, respondents from Croatia (ß=0.35; p < 0.001), Egyp...

It has been shown that inflammation reduces the effectiveness of sympathetic nerves in the regulation of knee joint blood flow, and the joint vascular- ß adrenoceptors are changed due to acute inflammation from a majority of ß-1 to an equality of ß-1 and ß-2 receptors.. To investigate the role of sympathetic nerves in nerve induced vasoconstriction and changes in joint vascular ß-adrenoceptors ...

Introduction: Beta-actin is a housekeeping gene, which is used as an internal standard in various biological studies. Recently, it was reported that the expression of commonly used housekeeping genes including ß–actin changes in disease states or under certain experimental conditions. Based on the reports about the effects of sex hormones on the expression of the ß- actin gene, in this study...

Abstract Funding Acknowledgements Type of funding sources: None. onbehalf PREDICT-VT Heart failure (HF) still develops in 4% up to 28% STEMI pts treated by pPCI, with the highest incidence first year. Accurate and early identification high-risk patients would allow targeted personalized intensive treatment . Aim current study is a sub-study (NCT03263949). Its aim define multi-parametric model f...