Recent lineage-tracing studies based on inducible genetic labelling have emphasized a crucial role for stochasticity in the maintenance and regeneration of cycling adult tissues. These studies have revealed that stem cells are frequently lost through differentiation and that this is compensated for by the duplication of neighbours, leading to the consolidation of clonal diversity. Through the c...

BACKGROUND As a result of the digital revolution coming to medicine, a number of new tools are becoming available and are starting to be introduced in clinical practice. OBJECTIVE We aim to assess health care professional and consumer attitudes toward new medical technology including smartphones, genetic testing, privacy, and patient-accessible electronic health records. METHODS We performe...

Vibrio parahaemolyticus, the leading cause of seafood-associated gastroenteritis, harbors two separate T6SSs on chromosomes 1 and 2, i.e., T6SS1 (VP1386-1420) and T6SS2 (VPA1025-1046). T6SS1 contains at least 7 putative operons: VP1386-1387, VP1388-1390, VP1392-1391, VP1393-1406, VP1400-1406, VP1409-1407, and VP1410-1420. V. parahaemolyticus AphA and OpaR are the two master regulators of quorum...

Although cortical neurons with similar functional properties often cluster together in a columnar organization, only ocular dominance columns, the columnar structure representing segregated anatomical input (from one of the two eyes), have been found in human primary visual cortex (V1). It has yet to be shown whether other columnar organizations that arise only from differential responses to st...

We take an experience of educational failure in school mathematics to illustrate the liberal capitalist ideology at work in educational institutions. This will be done by means of confronting the official discourse, which posits inclusion and equity as fundamental goals of mathematics education, with its actualization within a secondary school, whose student-intake can be labeled as marginalise...

Human pluripotent stem cells (hPSC) have the potential to become important tools for the establishment of new models for in vitro drug testing of, for example, toxicity and pharmacological effects. Late-stage attrition in the pharmaceutical industry is to a large extent caused by selection of drug candidates using nonpredictive preclinical models that are not clinically relevant. The current he...

background: psychological and behavioral domains are important in coping with type ii diabetes. this study was conducted to assess supportive and coping obstacles in living with type ii diabetes among patients who visited hospitals affiliated to tehran university of medical sciences (tums). methods: this was a cross-sectional study with 600 subjects who participated in the study. data collectio...

evaluation of urmia medical university faculty member views about research obstacles r salem safy ,ma bn ashraf rezaei ,?bsc r sadatian , msc z moshirie , msc n sheikhy , a baniadam , msc received: 7april, 2009 accepted: 27 july, 2009 abstract background & aims: identifying research obstacles, assessment of faculty members’ ability in research skills and faculty members’ satisfaction of researc...