Abstract Background and Aims The use of multiple markers may improve the accuracy in glomerular filtration rate (GFR) estimation especially when interpretation creatinine cystatin C is limited. We sought to externally validate a recently developed multi-marker nuclear magnetic resonance (NMR)-based estimated GFR equation (eGFR-NMR) using biracial Genetic Epidemiology Network Arteriopathy cohort...

abstract   background: squamous cell carcinoma (scc) constitutes the main oral malignancy . parallel to better understanding of molecular and genetic patterns of tumor behavior, more precise correlation of tumor markers such as epidermal growth factor (egf) and laminin-5 are sought to estimate macroscopic and microscopic tumor status .   methods: we conducted a cross-sectional study collecting ...

Functional foods have emerged as a new approach to improve human health in term of nutraceutical to prevent people from illness rather than cure patients though medical treatment. In Asian society, particularly in Thailand, the utilizations of functional ingredients have been integrated in every parts of ordinary life. In this study, the tyrosine kinase activity of epidermal growth factor recep...

Functional foods have emerged as a new approach to improve human health in term of nutraceutical to prevent people from illness rather than cure patients though medical treatment. In Asian society, particularly in Thailand, the utilizations of functional ingredients have been integrated in every parts of ordinary life. In this study, the tyrosine kinase activity of epidermal growth factor recep...

EGFR-TKIs (tyrosine kinase inhibitor) can effectively improve the survival rate of NSCLC patients with EGFR sensitive mutations. However, concomitant alterations along mutations often affect effect EGFR-TKIs. The genome characteristic co-mutation is great significance for guiding clinical treatment. In this study, we first reported genetic characteristics EGFR/RB1/TP53 co-variation in Chinese n...

Epidermal growth factor receptor (EGFR) is one of signalling pathways activated during premalignant proliferative changes in the airway epithelium. However there is no agreement about prognostic significance of EGFR expression in non-small cell lung cancer (NSCLC). Facts mentioned above prompted us to study EGFR expression in the group of 78 surgically treated squamous cell lung cancer (SqCLC) ...

BACKGROUND/AIMS We have reported that the eGFR overestimates renal function when glycemic control is poor. It has been reported that eGFR calculated by serum creatinine underestimates GFR in living kidney donors. We compared the utility of the eGFR in diabetic patients, non-diabetic patients and living kidney donors. Forty diabetic patients, 40 non-diabetic patients, and 40 living kidney donors...