times that needed to denature egg albumin, using the estimate given by Mirskyl2 or fifty times the energy needed for the inactivation of certain ionic forms of pepsin according to Steinhardt's determinations."3 The denaturation of egg albumin by ultra-violet light is a first order reaction,'4 i.e., the survival curve is a straight line similar to that obtained for chromosome abnormalities. It s...

Methanolic extract of Heteropogon contortus (L.) Beauv was screened for Bronchorelaxation (in vitro anti-histaminic) and in vivo anti-inflammatory effects. Bronchorelaxation effect was evaluated in terms of inhibition of histamine and acetylcholine induced contraction in guinea pig tracheal chain. Anti-inflammatory effect was assessed using carrageenan and egg albumin induced inflammation in ra...

1. Antisera have been produced in chickens with specific precipitates from Type II pneumococcus horse and rabbit antisera. 2. Specific precipitates from anti-Types I and II pneumococcus horse sera removed the same amount of antibody from the chicken anti-horse specific precipitate serum. Specific precipitates from horse antisera to diphtheria toxin and to crystalline egg albumin removed about o...

Serial studies of the serum levels of trypsin inhibitor have been performed on monkeys following injection of turpentine-falba, total body irradiation, thermal injury, splenectomy, administration of cortisone acetate and egg albumin. Following the injection of turpentine-falba mixture there was a prompt elevation in the trypsin inhibitor power of the serum. A similar response accompanied the ad...

Recent studies on the digestion of proteins by the proteolytic enzymes of the gastrointestinal tract have resulted in a considerable revision of our concepts on how these enzymes act. Tiselius and Eriksson-Quensel (1) studied the mechanism of the peptic digestion of crystalline egg albumin by electrophoretic examination of the products of proteolysis. They observed that, as digestion proceeded,...

A few years ago it was found ls2 that the effect of pure gelatin and crystalline egg albumin on the conductivity of a 0.6 per cent NaCl solution is dependent on the hydrogen ion concentration. Additional increments of protein increased total conductivity when the proteins were highly ionized (pH 3.3) and decreased it when they were relatively less ionized (pH 5.1 and 7.4). At the reaction of hu...

1. Egg albumin when injected into an ameba or discharged into the solution about it raises the apparent pH of the cytoplasm of the ameba. 2. With time the cytoplasm returns to the original pH 6.9 if the nucleus is present. Amebae that have received repeated injections of albumin in some cases extrude their nuclei. In these cells the cytoplasm remains at the more alkaline pH induced by the album...