AIMS Previous studies using isolated strips of human detrusor muscle identified adjustable preload tension, a novel mechanism that acutely regulates detrusor wall tension. The purpose of this investigation was to develop a method to identify a correlate measure of adjustable preload tension during urodynamics. METHODS Patients reporting urgency most or all of the time based on ICIq-OAB survey...

This paper examines how estimates of the price elasticity of demand for beer vary with the choice of alcohol price series examined. Our most important finding is that the commonly used ACCRA price data are unlikely to reliably indicate alcohol demand elasticities-estimates obtained from this source vary drastically and unpredictably. As an alternative, researchers often use beer taxes to proxy ...

PURPOSE To determine the clinical efficacy of corneal elasticity (CE) measurements as an index of intra-ocular pressure(IOP). The considerable body of evidence linking elevated intra-ocular pressure (IOP) to glaucomatous conditions, points to the importance of the accurate and reliable measurement of IOP for diagnosis, prevention and post treatment assessments. Recently an applanation resonator...

The modern supply chain were more vulnerable to risk, supply chain risk mainly comes from many aspects of the internal and external environment, the supply chain industry products background, upstream and downstream supply chain relationship, decision support. The study found that the need to establish information sharing mechanism, multilevel supply chain defense system, the principal-agent me...

Bacteria often inhabit and exhibit distinct dynamical behaviors at interfaces, but the physical mechanisms by which interfaces cue bacteria are still poorly understood. In this work, we use interfaces formed between coexisting isotropic and liquid crystal (LC) phases to provide insight into how mechanical anisotropy and defects in LC ordering influence fundamental bacterial behaviors. Specifica...

This paper aims to develop a new bi-level game model for joint pricing and inventory decisions in competitive supply chain consisting of dominant manufacturer, who produces single perishable product from deteriorating raw materials, two follower retailers face nonlinear price-dependent demand operate under Cournot assumptions. Three levels warehousing including material warehouse, final retail ...

Fine-grained elasticity control of cloud services has to deal with multiple elasticity perspectives (quality, cost, and resources). We propose a cloud services elasticity control mechanism that considers the service structure for controlling the cloud service elasticity at multiple levels, by firstly defining an abstract composition model for cloud services and enabling multi-level elasticity c...

-A general formalism for Metabolic Control Analysis is derived using general sensitivity analysis and structural information of the metabolic pathway inherent in the stoichiometry matrix. The equations derived provide a general procedure for calculating the control coefficients from the elasticity coefficients using matrix algebra, and is valid for any pathway stoichiometry. The procedure dimin...

Understanding the precise nature of price sensitivities at the individual policyholder level is extremely valuable for insurers. A rate increase has a direct impact on the premium customers are paying, but there is also the indirect impact as a result of the ‘‘causal’’ effect of the rate change on the customer’s decision to renew the policy term. A rate increase may impair its intended impact o...