A case of cardiomyopathy with systemic emboli is reported. Two dimensional and M-mode echocardiography showed abnormal intracavitary echoes. After further systemic emboli, echocardiograms showed the complete disappearance of the abnormal echoes found previously in the apex, which suggested that the emboli resulted from detachment of the left ventricular mural thrombi.

BACKGROUND Traditional pharmacological therapies aiming to modify the abnormal electrophysiological substrate underlying cardiac arrhythmias may be limited by their relatively low efficacy, global cardiac activity, and significant proarrhythmic effects. We suggest a new approach, in which transfected cellular grafts expressing various ionic channels may be used to manipulate the local electroph...