The purpose of this document is to specify the basic data types required for storing electrophysiology and optical imaging data to facilitate computer-based neuroscience studies and data sharing. These requirements are being developed within a working group of the Electrophysiology Task Force in the International Neuroinformatics Coordinating Facility (INCF) Program on Standards for Data Sharin...

The field of cardiac electrophysiology tries to abstract, describe and finally model the electrical characteristics a heartbeat. With recent advances in electrophysiology, models have become more powerful descriptive as ever. However, advance inverse electrophysiological modeling, i.e. creating from measurements such ECG, less investigated smoothness simulated ECGs w.r.t. parameters need be fur...

Electrophysiology, the ‘gold standard’ for investigating neuronal signalling, is being challenged by a new generation of optical probes. Together with new forms of microscopy, these probes allow us to measure and control neuronal signals with spatial resolution and genetic specificity that already greatly surpass those of electrophysiology. We predict that the photon will progressively replace ...

We discuss the application of the spectral element method to the monodomain and bidomain equations describing propagation of cardiac action potential. Models of cardiac electrophysiology consist of a system of partial differential equations coupled with a system of ordinary differential equations representing cell membrane dynamics. The solution of these equations requires solving multiple leng...

i b h e o w m i n V n S t o o h r p fi a A e t r A a a V he advances in cardiac electrophysiology during 2003 will e divided into three basic categories: mechanisms, genetics, nd therapy, the latter including ablation, devices, drugs, and unique pacing application in heart failure. This brief ummary is not a comprehensive review article, and cannot o justice to all the efforts and many publicat...

Mathematical modeling has been used for over half a century to advance our understanding of cardiac electrophysiology and arrhythmia mechanisms. Notably, computational studies using mathematical models of the cardiac action potential (AP) have provided important insight into the fundamental nature of cell excitability, mechanisms underlying both acquired and inherited arrhythmia, and potential ...

Tachycardias that are successfully ablated in the vicinity of the atrioventricular (AV) node are common, and although frequently successfully treated, are among the most difficult arrhythmias to understand in cardiac electrophysiology. Even AV node reentrant tachycardia (AVNRT), despite near universal cure, is complex with the anatomic constructs for typical, atypical forms, left-sided AVNRT, u...

This two-part manuscript reviews diagnostic pacing maneuvers for supraventricular tachycardia (SVT). Part one will involve a detailed consideration of ventricular overdrive pacing (VOP), since this pacing maneuver provides the diagnosis in the majority of cases. This will include a review of the post-VOP response, fusion during entrainment, the importance of the VOP site, quantitative results o...