Introduction: Approximately 20% of healthcare workers in high-income countries such as Australia, Canada and the USA work in rural areas. Healthcare workers are known to be vulnerable to occupational injury and poor work disability outcomes; given their rural–urban distribution, it is possible to compare work disability prevention in rural and urban areas. However, little attention has been pai...

METHODS: A literature search of Medline, Embase, PsychINFO, Web of Science, PubMed, and conference Web sites (1990–March 2011) using the search terms, infant, child, HIV, neurodevelopment, cognition, language, and antiretroviral therapy, identified 31 studies of HIV/ antiretroviral exposure using standardized tools to evaluate infant/ child development as the main outcome. Articles were include...

t is increasingly recognized that health care decision-making around the world needs to be informed by high quality and timely research evidence. The randomized controlled trial (RCT) has long been considered the “gold standard” in the hierarchy of evidence; randomized trials, involving sufficient numbers of participants, are essential to distinguish reliably between the effects of health care ...

BACKGROUND Reporting of adverse events in randomized clinical trials (RCTs) is encouraged by the authors of The Consolidated Standards of Reporting Trials (CONSORT) statement. With robust methodological design and adequate reporting, RCTs have the potential to provide useful evidence on the incidence of adverse events associated with spinal manipulative therapy (SMT). During a previous investig...

The design and application of hyaluronic acid (HA)-based scaffolds to control cell response and construct ideal tissue engineering products have been of great interest in the past few decades. This review provides an overview of the biological properties of HA to better understand how to engineer a cell-scaffold composite that is qualified in tissue engineering; important tissue engineering app...

Physicians are practicing in an era in which they are often expected to write business plans in order to acquire, develop, and implement new technology or programs. This task is yet another reminder of the importance of business principles in providing quality patient care amid allocation of increasingly scarce resources. Unfortunately, few physicians receive training during medical school, res...

There are a growing number of studies concerning people with intellectually disabilities (ID) who offend, however few studies systematically record prevalence of mental health problems. This article will attempt to determine the prevalence mental health problems in people with ID who offend. Search terms were entered into the CINAHL, EMBASE, Ovid MEDLINE(R) and PsycINFO databases. Studies were ...

METHODS: A literature search of Medline, Embase, PsychINFO, Web of Science, PubMed, and conference Web sites (1990–March 2011) using the search terms, infant, child, HIV, neurodevelopment, cognition, language, and antiretroviral therapy, identified 31 studies of HIV/ antiretroviral exposure using standardized tools to evaluate infant/ child development as the main outcome. Articles were include...

Methods We searched MEDLINE, EMBASE, and the Cochrane Controlled Trials Register, from their beginning to September 2012, and screened the references of the already included studies. We reviewed randomised clinical trials comparing surgery with a placebo intervention. Surgery was defined as any procedure that changes the anatomy and requires a skin incision or the use of endoscopic techniques; ...

Background and Purpose—Based on the results of animal experiments, clinical trials were performed with nimodipine, which did not demonstrate a beneficial effect on outcome after stroke. The aim of this study was to determine whether the evidence from animal experiments with nimodipine supported the use of nimodipine in clinical trials. Methods—We performed a systematic review of animal experime...