Method: Ten electronic databases including MEDLINE and EMBASE (1980 to February 2006), and bibliographies of included articles were searched without language restrictions. Studies comparing effects of coronary revascularization and medical management before noncardiac surgery were included. Patient outcome data including perioperative mortality, myocardial infarction, long-term mortality, or la...

Honey has been extensively studied in the treatment of wound but efficacy in clinical practice is not fully established. The aim of the present study was to evaluate the efficacy of topical application honey in observational studies as well as in controlled clinical trials in the treatment of wound healing. A systematic literature search was carried out from 1966 to 31 July 2008 in Pubmed, Medl...

Dietary Zn recommendations vary widely across Europe due to the heterogeneity of approaches used by expert panels. Under the EURopean micronutrient RECommendations Aligned (EURRECA) consortium a protocol was designed to systematically review and undertake meta-analyses of research data to create a database that includes ‘best practice’ guidelines which can be used as a resource by future panels...

Once used only as third-line therapy in the management of chronic pain states, methadone is now being used as firstand second-line therapy. Most risks and the stigma associated with methadone use have been known for years. Only over the past decade or so have the unique pharmacokinetic-pharmacodynamic properties and methods for conversion from other opioids to methadone been established. Pertin...

Introduction: Emergency dispatch is a relatively new field, but the growth of dispatching as a profession, along with raised expectations for help before responders arrive, has led to increased production of and interest in emergency dispatch research. As yet, no systematic review of dispatch research has been conducted. Objective: This study reviewed the existing literature and indicated gaps ...

OBJECTIVE: In order to provide an overview of current knowledge, the literature was systematically examined for clinical studies, which evaluate the safety and effectiveness of bosentan in pediatric pulmonary arterial hypertension (PAH). SOURCES: 3 databases (MEDLINE, EMBASE and BIOSIS) were searched for the period January 2000 October 2007 using the key words 'pulmonary arterial hypertension',...

BACKGROUND Previously, we reported on the low recall of Google Scholar (GS) for systematic review (SR) searching. Here, we test our conclusions further in a prospective study by comparing the coverage, recall, and precision of SR search strategies previously performed in Embase, MEDLINE, and GS. METHODS The original search results from Embase and MEDLINE and the first 1000 results of GS for l...

Objective To evaluate the effects of standalone versus clinically integrated teaching in evidence based medicine on various outcomes in postgraduates. Design Systematic review of randomised and non-randomised controlled trials and before and after comparison studies. Data sources Medline, Embase, ERIC, Cochrane Library, DARE, HTA database, Best Evidence, BEME, and SCI. Study selection 23 studie...

This paper provides a systematic review of the literature about prostate cancer risk associated with testosterone therapy for hypogonadism. A comprehensive search of MEDLINE, EMBASE and other resources was conducted to identify articles that highlight occurrences of prostate cancer in men receiving testosterone therapy for hypogonadism treatment. Articles that met study inclusion criteria were ...

Methods Search Strategy We searched the Cochrane Stroke Group Trials Register (last searched June 2003). In addition, the following electronic databases were searched: Cochrane Central Register of Controlled Trials (Cochrane Library, Issue 4, 2002), MEDLINE (1966 to December 2002), EMBASE (1980 to December 2002), CINAHL (1982 to December 2002), SPORTDiscus (1949 to December 2002), Science Citat...