Hydrophobic helical peptides interact with lipid bilayers in various modes, determined by the match between the length of the helix's hydrophobic core and the thickness of the hydrocarbon region of the bilayer. For example, long helices may tilt with respect to the membrane normal to bury their hydrophobic cores in the membrane, and the lipid bilayer may stretch to match the helix length. Recen...

The use of orphan G protein-coupled receptors (GPCRs) as targets to identify new transmitters has led over the last decade to the discovery of 12 novel neuropeptide families. Each one of these new neuropeptides has opened its own field of research, has brought new insights in distinct pathophysiological conditions and has offered new potentials for therapeutic applications. Interestingly, sever...

Within the framework of an isospin-dependent Boltzmann-Uehling-Uhlenbeck (BUU) model using initial proton and neutron densities calculated from the nonlinear relativistic mean-field (RMF) theory, we compare the strength of transverse collective flow in reactions Ca + Fe and Cr + Ni, which have the same mass number but different neutron/proton ratios. The neutron-rich system (Ca+Fe) is found to ...

Cu(100), Cu(110), Ag(111},Au(111), and Au(100}), a semimetal [Sb(100}],and a layered compound {1T-TiS2). Data for Au{111) show that image-potential states exist even in the presence of bulk states. The coupling with bulk states is weak as indicated by the narrow {&0.1 eV) width of the image states. The binding energies of the lowest state cluster around 0.7 eV for a variety of metal and semimet...

The epidemics of obesity and diabetes have aroused great interest in the analysis of energy balance, with the use of organisms ranging from nematode worms to humans. Although generating energy-intake or -expenditure data is relatively straightforward, the most appropriate way to analyse the data has been an issue of contention for many decades. In the last few years, a consensus has been reache...

The suppression of reproductive function is known to occur in women engaging in activities that require high energetic expenses, such as sport participation and subsistence work. It is still unclear, however, if reproductive suppression is a response to high levels of energy expenditure, or only to the resulting state of negative energy balance. To our knowledge, this study provides the first e...

Obesity has become, nowadays, a global concern affecting both developed and developing countries. Nutrition and physical activity represent the major factors influencing energy balance and subsequently weight status. Deciding toward an appropriate intake of all nutrients is seen as necessary to maintain a wholesome lifestyle: among nutrients, sugar plays a major role and its consumption has lon...