Abstract: The genome sequencing as well the protein structure and function of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is known helps in structurally characterizing viral proteins, determining evolutionary trajectories, identifying interactions with host proteins providing biological insights. Knowledge SARS-CoV-2 useful a means understanding disease 19 (COVID-19). This stud...

high morbidity and mortality of influenza virus infection makes it an important disease world-wide. mouse is a very well-studied animal model for this disease with similar manifestation to human disease. it would be desirable to induce mucosal as well as circulating immune responses to obtain protection from infection and to decrease the spread of the virus. cell mediated immunity (proliferativ...

It has been clearly established that the budding of the human immunodeficiency virus (HIV-1), a lentivirus, occurs specifically through the basolateral membrane in polarized epithelial cells. More recently, the signal was assigned to a tyrosine-based motif located in the intracytoplasmic domain of the envelope glycoprotein, as previously observed on various other viral and cellular basolateral ...