The mitochondrial chaperonin Hsp60 is a ubiquitous molecule with multiple roles, constitutively expressed and inducible by oxidative stress. In the brain, Hsp60 is widely distributed and has been implicated in neurological disorders, including epilepsy. A role for mitochondria and oxidative stress has been proposed in epileptogenesis of temporal lobe epilepsy (TLE). Here, we investigated the in...

Objective: To compare the emotional structure and coping strategies in patients with psychogenic non epileptic seizures, epilepsy and control group. Methods: Among patients with complaining of epilepsy attacks that referred to clinic of Imam Reza (Peace be upon him) in Shiraz, 30 patients with psychogenic non epileptic seizures and 30 patients with epilepsy were selected .A total of 30 patients...

Five patients with acute anoxic episodes requiring resuscitation, with coma and development of epileptic manifestations are reported. Myoclonic types of seizures were predominantly seen in these cases. Rhythmical or burst-like generalized-synchronous spike discharges represented the most common EEG correlate of the epileptic activity. In one patient, a suppression-burst-like pattern was tempora...

Objective: To compare the emotional structure and coping strategies in patients with psychogenic non epileptic seizures, epilepsy and control group. Methods: Among patients with complaining of epilepsy attacks that referred to clinic of Imam Reza (Peace be upon him) in Shiraz, 30 patients with psychogenic non epileptic seizures and 30 patients with epilepsy were selected .A total of 30 patients...

objective: to compare the emotional structure and coping strategies in patients with psychogenic non epileptic seizures, epilepsy and control group. methods: among patients with complaining of epilepsy attacks that referred to clinic of imam reza (peace be upon him) in shiraz, 30 patients with psychogenic non epileptic seizures and 30 patients with epilepsy were selected .a total of 30 patients...

Kainic acid (KA) is well known as a chemical compound to study epileptic seizures and neuronal excitotoxicity. KA-induced excitotoxicity causes neuronal death by induction of autophagic stress and microglia-derived neuroinflammation, suggesting that the control of KA-induced effects may be important to inhibit epileptic seizures with neuroprotection. Naringin, a flavonoid in grapefruit and citr...

oxidative stress has been suggested as a consequence and as a cause of epileptic seizures. researches indicate achillea wilhelmsii (a.wilhelmsii) has anti-oxidant and anti-spasmic effects on central nervous system. this plant grows in most part of iran. an iranian research that done in 2013 showed that the hydroalcoholic extract of achillea wilhelmsii possesses an antioxidant effect in the brai...

The occurrence of seizures is the common feature across the spectrum of epileptic disorders. We describe how the use of mechanistic neural population models leads to novel insight into the dynamic mechanisms underlying two important types of epileptic seizures. We specifically stress the need for a spatio-temporal description of the rhythms to deal with the complexity of the pathophenotype. Ada...

OBJECTIVE Our purpose was to present and discuss the psychiatric diagnoses of patients who presented psychogenic non-epileptic seizures (PNES) during video-electroencephalographic monitoring (VEEG). METHODS Out of 98 patients, a total of 28 patients presented PNES during the diagnostic procedure. In those cases in which the PNES that occurred during VEEG were validated by clinical history (cl...