background: the activity and toxicity of etoposide in women with recurrent ovarian cancer was evaluated in a case series of women with recurrent ovarian cancer who had measurable disease, methods: all patients had plior platinum-based chemotherapy and developed progressive disease, etoposide was given as 50mg/day for 21 days every 4 weeks until progression of disease or prohibitive toxicity, be...

background: magnetized water has made many improvements in industry, agriculture and medicine. however its utilization in medicine still remains controversial. objective:  in this study we aimed to investigate the effects of magnetized water on height of epithelial cells in pre-implantation stage endometrium and fallopian tube and number of corpus lutea in female mice. materials and methods:  e...

background: despite the extensive information available in the literature, cell surface marker signature of human amniotic epithelial cells (haecs) remains controversial. the aim of the present study was to characterize immuno-phenotypic features, proliferative capacity and immunogenicity of haecs. we also tested whether expression of some cell surface markers is influenced by the type of tryps...

Abstract The gut immune system consists of three lines defense systems: barriers, innate immunity and adaptive or acquired that work together to give ruminant gastrointestinal tract (GIT) protection from disease. is the largest organ body. mucosal barrier- tight junctions “kill zone” along with mucosa maintaining an “anti-inflammatory” state are essential for “good health”. microbiome- microorg...

Acidic airway microenvironment is one of the representative pathophysiological features of chronic inflammatory respiratory diseases. Epithelial barrier function is maintained by TJs (tight junctions), which act as the first physical barrier against the inhaled substances and pathogens of airway. As previous studies described, acid stress caused impaired epithelial barriers and led the hyperper...

the main purpose of this study was to investigate the major barriers to application of good agricultural practices (gaps) technologies in sustainability of livestock by ranchers of meshkinshahr. a sample of 120 farmers was selected by using proportional random sampling method. data were collected by means of a questionnaire. validity of questionnaire was determined through agricultural jihad ex...

introduction epithelial rejection typically begins in a linear pattern from the periphery of the graft and progresses centripetally. here in, we reported a patient with a new presentation of corneal epithelial graft rejection. case presentation a 23-year-old man presented with blurred vision two months after penetrating keratoplasty. conclusions slit lamp examination revealed sharply demarcated...

primary de novo intraosseous carcinoma is a rare neoplastic lesion which commonly occurs in the jaws. it is an epithelial odontogenic malignancy arising from odontogenic epithelial residues in the bone rather than from a preexisting epithelial lesion. in the present case report, the clinical, radiological and histological features of primary de novo intraosseous carcinoma are discussed and its ...

The human neutrophil is a professional phagocyte of fundamental importance for defense against microorganisms, as witnessed by the life-threatening infections occurring in patients with neutropenia or with defects that result in decreased microbicidal activity of the neutrophil. Likewise, the skin and mucosal surfaces provide important barriers against infections. Traditionally, these major def...