A facile one-pot two-step process for the synthesis of 1,3-thiazole heterocycles via organocatalytic epoxidation of nitro-olefins with the t-BuOOH/DBU system, and subsequent reaction of α-nitro-epoxides with thioamides under mild conditions has been developed.

The structure of the most recently discovered, biologically highly active prostaglandin, PGI2 or prostacyclin, is correctly predicted on biogenetic grounds, and a general synthesis starting with prostaglandins of the F2alpha series is reported. Starting with the biologically active 13,14-dehydro-PGF2alpha, the synthesis involves formation of a 5-bromo-6,9alpha-epoxy derivative, followed by este...

I point out the existence of a theoretical difficulty that underlies the curve segmentation problem studied by Rosin and West and present a possible solution to it.

UNLABELLED In the present work, ion-conductive hybrid organic-inorganic polymers based on epoxy oligomer of diglycide aliphatic ester of polyethylene glycol (DEG) and lithium perchlorate (LiClO4) were synthesized. The effect of LiClO4 content on the electrophysical properties of epoxy polymers has been studied by differential scanning calorimetry (DSC) and broadband dielectric spectroscopy (BDS...

Epoxyeicosatrienoic acids (EETs) are endothelium-derived eicosanoids that activate potassium channels, hyperpolarize the membrane, and cause relaxation. We tested 19 analogs of 14,15-EET on vascular tone to determine the structural features required for activity. 14,15-EET relaxed bovine coronary arterial rings in a concentration-related manner (ED(50) = 10(-6) M). Changing the carboxyl to an a...

The curing of epoxy-anhydride vitrimers involves anionic copolymerization epoxide and anhydride along with homopolymerization excess epoxide, giving rise to a poly(ester-co-ether) network. By monitoring using infrared spectroscopy in different conditions mapping the presence OH groups, we demonstrate that generation hydroxide necessary for transesterification, exclusively relies on side reactio...

Dimethylnorbornene ester (DNE) is successfully used as a noncovalent adhesion promoter. DNE was confirmed to copolymerize with dicyclopentadiene (DCPD) to yield a copolymer with better adhesion to an EPON 828 epoxy matrix relative to poly(DCPD) alone. The mechanical properties of the copolymer were comparable to that of poly(DCPD) alone. An optimized blend of the monomers was encapsulated using...

The suitability of various peroxide initiators for a radical polymerization-based self-healing system is evaluated. The initiators are compared using previously established criteria in the design of ring opening metathesis polymerizationbased self-healing systems. Benzoyl peroxide (BPO) emerges as the best performing initiator across the range of evaluation criteria. Epoxy vinyl ester resin sam...