U.v. irradiation of SH-RP cells, a lymphoblastoid cell line carrying EpsteinBarr virus, which was derived from a patient with acute myeloid leukaemia, retarded cell growth but significantly enhanced the percentage of cells containing virus-capsid antigen (VCA) as demonstrated by indirect immunofluorescence. The effects of u.v. irradiation on SH-RP cultures were reversible under normal condition...

A 58-year-old healthy woman suffered from headache and high fever above 38°C. At three days after symptom onset, she noticed speech disturbance. On the following day, she was admitted to our hospital because of gait disturbance and exacerbation of the speech disturbance. On admission, her body temperature was 37.5°C. Neurological examinations disclosed ataxic dysarthria, limb ataxia and wide-ba...

conclusions w. coagulans inhibits the development of bph can be useful for the treatment of this condition. results the present study revealed that bph caused elevation of mda levels, suppression of tac levels, and increased pcna expression in the prostate gland. interestingly, in a dose-dependent manner, wce caused decreased mda levels and increased tac levels in the prostate gland, compared t...

A monoclonal antibody, selected for reactivity with the EpsteinBarr virus (EBV)-encoded antigen EBNA-1, exhibited strong reactivity with the synovial lining cells in joint biopsies from 10 of 12 patients with rheumatoid arthritis (RA) and adherent cells eluted from these tissues. No staining of RA synovial membrane frozen tissue sections or eluted synovial-lining cells was obtained with monoclo...

Epstein-Barr Virus (EBV) is a human herpesvirus, infecting 95% of humans, that is causally associated with the benign B-cell proliferative disorder, infectious mononucleosis. EBV has also been etiologically associated with several cancers, such as Burkitt's lymphoma, AIDSrelated immunoblastic lymphomas, post-transplant lymphomas, nasopharyngeal carcinoma, and gastric carcinoma. Very few viral g...

Introduction. The discovery of two types EpsteinBarr virus (EBV) (EBV-1 and EBV-2) that have different biological properties stimulated the search for neoplasms associated with each type virus.
 aim work is to study nature association nasopharyngeal cancer (NPC) EBV-1 EBV-2, serological activity viral concentration EBV DNA in blood plasma gender, age ethnic groups NPC patients represent ge...

Background: E-cadherin is a trans-membrane glycoprotein that plays a critical role in many aspects of cell adhesion as well as establishment and maintenance of epithelial cell polarity. Loss of the adhesive function of E-cadherin seems to promote invasive and metastatic properties of neoplastic cells. Objectives: The present study is a retrospective study aiming to evaluate the loss of E-cadher...

Oncogenic anaplastic lymphoma kinase (ALK) fusion proteins (NPM/ALK and associated variants) are expressed in about 60% of anaplastic large cell lymphomas (ALCLs) but are absent in normal tissues. In this study, we investigated whether ALK, which is expressed at high levels in lymphoma cells, could be a target for antigen-specific cell-mediated immunotherapy. A panel of ALK-derived peptides was...