UNLABELLED The aim of this study was to determine the prevalence of ESBL-producing Escherichia coli and Klebsiella pneumoniae as well as genes encoding ESBLs. MATERIAL AND METHODS A total of 1207 non-repeat isolates of E. coli and K. pneumoniae were obtained from urine, tracheal aspirate, wound swab and blood from patients hospitalized at the University Clinics in Skopje. ESBL set and E-test ...

BACKGROUND In recent years, the world has seen a surge in extended-spectrum β-lactamase (ESBL)-producing bacteria. However, data on the dissemination of ESBL-producing Enterobacteriaceae in the community from systematically enrolled study subjects in Africa remains limited. To determine the prevalence, phenotypic resistance patterns and genetic characteristics of ESBL-producing E. coli and K. p...

BACKGROUND The spread of Extended-Spectrum beta (β)-Lactamases (ESBL)-producing Enterobacteriaceae has become a serious global problem. ESBL-producing Enterobacteriaceae vary based on differences in antibiotic use, nature of patients and hospital settings. This study was aimed at determining ESBL and antibiogram in Enterobacteriaceae isolates from clinical and drinking water sources in Bahir Da...

BACKGROUND The number of extended-spectrum beta-lactamase (ESBL) positive (+) Escherichia coli is increasing worldwide. In contrast with many other multidrug-resistant bacteria, it is suspected that they predominantly spread within the community. The objective of this study was to assess factors associated with community-acquired colonization of ESBL (+) E. coli. METHODS We performed a matche...

BACKGROUND Plasmid-encoded extended-spectrum beta-lactamase (ESBL)-enzymes are frequently produced by Escherichia coli. Several ESBL-plasmids contain genes for toxin-antitoxin (TA) systems, which assure the maintenance of plasmids in bacteria and prevent the cells from "post-segregational killing". These systems limit options to "cure" plasmids of ESBL-wild-type strains due to the death of the ...

OBJECTIVE To assess the co-colonization rates of extended-spectrum beta-lactamase (ESBL)-producing bacteria and vancomycin-resistant Enterococcus (VRE) obtained on active surveillance cultures. DESIGN Prospective cohort study. SETTING Medical and surgical intensive care units (ICUs) of a tertiary-care hospital. PATIENTS Patients admitted between September 2001 and November 2002 to the med...

BACKGROUND The spread of Extended Spectrum β-lactamases (ESBLs) among Enterobacteriaceae and other Gram-Negative pathogens in the community and hospitals represents a major challenge to combat infections. We conducted a study to assess the prevalence and genetic makeup of ESBL-type resistance in bacterial isolates causing community- and hospital-acquired urinary tract infections. METHODS A to...

Background: Infection caused by ESBL in the surgical site infection is very alarming. Objective: The purpose of the present study was to see the status of ESBL bacteria isolated from surgical site infection with their antimicrobial sensitivity pattern. Methodology: This cross sectional study was conducted in the Department of Microbiology at Dhaka Medical College, Dhaka from January, 2005 to De...

Urinary tract infection (UTI) is a common and painful human illness that, unfortunately not responsive to commonly used antibiotics in current practice. The role of fosfomycin and nitrofurantoin in the era of growing bacteria resistance has been widely discussed. In this study, we aimed to know the local antimicrobial susceptibilities, fosfomycin and nitrofurantoin susceptibility in particular,...

INTRODUCTION The emergence of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli has become an important challenge among pediatric patients with community-acquired urinary tract infection (UTI). OBJECTIVES The aim of this study was to assess the antimicrobial susceptibility patterns, associated risk factors and to survey the frequency of bla cefotaximase (CTX-M), bla temoneira...