نتایج جستجو برای: esbls
تعداد نتایج: 1159 فیلتر نتایج به سال:
Extended spectrum beta lactamase (ESBL)-producing organisms pose unique challenge to clinical microbiologists, clinicians, infection control professionals and scientists. ESBLs are enzymes produced by some bacteria or germs that can make them resistant to certain antibiotics. ESBLs are enzymes capable of hydrolyzing penicillin, broadspectrum cephalosporins and monobactams that are generally der...
Two clinical isolates of extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae were noted to be less susceptible than expected to imipenem. Both were missing outer membrane proteins that serve as channels for antibiotic entry. The role of beta-lactamase in resistance was investigated by eliminating the original ESBL and introducing plasmids encoding various ESBLs and AmpC beta...
INTRODUCTION While the Clinical and Laboratory Standards Institute (CLSI) recommends against routine screening for extended spectrum β-lactamases (ESBLs), knowledge of these data can provide valuable insights regarding epidemiology and drug therapy decisions. The purpose of this study was to compare the impact of minimum inhibitory concentration (MIC)-based screening versus phenotypic confirmat...
background clinical significance of extended-spectrum beta-lactamases (esbls) production in enterobacter spp. has not well been established. objectives this study was conducted to investigate the prevalence of esbls produced by enterobacter spp. in clinical isolates. materials and methods this descriptive cross-sectional study was performed during may 2010 to april 2012 in the city of sanandaj,...
BACKGROUND Extended-spectrum beta-lactamases (ESBLs) are a group of enzymes that hydrolyze antibiotics, including those containing new cephalosporins, and they are found in a significant percentage of Escherichia coli and Klebsiella pneumoniae strains. With the widespread use of antibiotics, difficulties with infection therapy caused by drug resistant organisms, especially those that have acqui...
Abstract: Background and objectives: Antibiotic resistant to Antimicrobial agents is one of the most important concern in hospitals, which can lead to increased costs, treatment fails and mortality rates. The aim of this study was identification of Gram-negative bacilli resistant to extended-spectrum β-lactamase Enzymes (ESBLs) and determination of the effect of silver nanoparticles on the...
سابقه و هدف: انواع مختلفی از بتالاکتامازهای وسیعالطیف (esbls) از قبیل blatem و blashv به طور برجسته در سویههای کلبسیلا حضور دارند. هدف از این مطالعه، بررسی فراوانی ژنهای blatem و blashv در سویههای کلبسیلا پنومونیه و اکسیتوکا مولد بتالاکتامازهای وسیعالطیف جداسازی شده از نمونه های ادراری در کرج بود. روش بررسی: از 100 ایزوله کلبسیلای جداسازی شده از نمونههای ادراری، باکتریهای مولد esbls...
s of the International Congress of Chemotherapy, Birmingham, England, 1999). In 1989 an outbreak of multiresistant Salmonella enterica serovar Typhimurium infections occurred in 12 of 14 Argentinian provinces. From these isolates a new non-SHV, non-TEM ESBL named CTX-M-2 was identified (26, 28, 29, 333). Organisms with CTX-M-2 have spread throughout many parts of South America (333). Other CTX-...
Twelve ceftazidime-resistant isolates of the family Enterobacteriaceae (11 Klebsiella pneumoniae isolates and 1 Escherichia coli isolate) were collected in 1995 from three Polish hospitals located in different cities. All were identified as producers of extended-spectrum beta-lactamases (ESBLs). Detailed analysis of their beta-lactamase contents revealed that six of them expressed SHV-5-like ES...
This review covers the recent findings on extended spectrum beta-lactamases (ESBL) pathogens, focusing on the epidemiology of infection due to this pathogen. Use of ESBL is growing rapidly and widely. CTX-M-15 producing ESBL Escherichia coli is the most commonly encountered in clinical practice. In general, ESBL infections are represented by urinary tract infections, but they can also cause fat...
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