5 SUMMARY The mycobacterial type VII secretion system ESX-1 is responsible for secretion of a number of proteins that play an important role during infection of the host. Regulation of expression of secreted proteins is often essential to establish a successful infection. Using transcriptome sequencing (RNA-seq), we found that abrogation of ESX-1 function in M. marinum leads to a pronounced inc...

In Spain, electrical industries do not charge the energy bill directly to the nal user, but they share the ownership of an enterprise (called R.E.E., Red El ectrica de Espa~ na) which gets all payments and then distributes them according to some complex criteria (amount of power generation of every company, number of customers, etc.) Recently, some of these companies have asked to redistribute ...

Enterohemorrhagic Escherichia coli (EHEC) exhibits a pattern of localized adherence to host cells, with the formation of microcolonies, and induces a specific histopathological phenotype collectively known as the attaching and effacing lesion. The genes encoding the products responsible for this phenotype are located on a 35-kb pathogenicity island designated the locus of enterocyte effacement,...

Resumen: El impresor antuerpiense Martín Nucio usó un pliego poético impreso en dos ediciones de 1546. Este está perdido, pero hay huella él tres posteriores. En este trabajo se delimita la relación estos impresos tardíos con el perdido y reconstruyen sus datos editoriales. Para ello, estudia filiación textual e iconográfica los poe...

El apiñamiento dental es una de las alteraciones más comunes debido a que el espacio disponible en bases óseas menor la suma total del tamaño los dientes, ocasionando un proble- ma oclusal, periodontal y estético, lo cual acrecienta necesidad tratamiento ortodóncico. objetivo este caso clínico dar opción eficaz para conseguir liberación apiñamiento, clase canina I bilateral, correcta intercuspi...