Although there have been several studies investigating a possible association between essential hypertension and TSC gene Arg904Gln polymorphisms, the results have been inconsistent. We conducted a meta-analysis of four case-control studies (one study in Europe and three studies in Asia), including 1811 essential hypertension cases and 1381 controls. The pooled results showed no significa...

AIMS/INTRODUCTION We aimed at estimating the prevalence and at identifying the frequent comorbidities of diabetes mellitus in a region of northeastern Italy from administrative health data. MATERIALS AND METHODS The prevalence was estimated according to two disease definitions, based on administrative health data. Association rule mining was used to detect comorbid diagnoses that coexisted wi...

In exploration of the association between pulse pressure and longevity in humans, 3 hypotheses are briefly discussed: the fetal origin hypothesis, antagonistic pleiotropy, and the telomere hypothesis of cellular aging. The implications of these hypotheses serve to draw a critical distinction between biologic age (aging) and chronological age and, thereby, offer an answer to a question that pres...

We analyzed the medical records of patients admitted to 11 hospitals over a 15-year period, looking for those with metabolically active sporadic pheochromocytomas (Group A) and those in whom the diagnosis was highly suspect but excluded (Group B). Fifty-three patients in Group A and 25 patients in Group B were found. We then devised a scoring system based on the presence or absence of typical s...

Direct arterial pressure and electrocardiogram have been measured continuously over a period of 24 hours in 15 patients. Observations have been made on the behaviour of these variables during 30 separate episodes of motor car driving. The patients were divided into three groups: (1) five normotensive subjects, (2) five patients with essential hypertension who were not receiving therapy, and (3)...

OBJECTIVES To evaluate the quantitative effects of the drug price reduction on pharmaceutical expenditures and the new guidelines to restrict prescribing on drug utilisation for antihypertensive drugs. DESIGN We used an interrupted time series design with the National patient sample data of Health Insurance Review and Assessment Service in South Korea. METHODS 54,295 participants who were w...

a single group, and the major part of our knowledge has been derived from retrospective analysis or cross-seetional studies of presumably normal populations. These limited observations have led to conflicting interpretations concerning the nature of hypertension and the importance of various factors in its pathogenesis. Pickering has challenged the classical concept that essential hypertension ...

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Page 1 of 1 EHT http://e-eht.org/ We found an error in our published article: In Table 6, ...

1. The complement 3 (C3) phenotype distribution in 112 patients with essential hypertension was compared with the distribution of 316 normotensive control subjects. 2. A significant increased frequency of the C3F-gene was found among the patients (0.2637 vs 0.1721, P = 0.0031), indicating an association between the C3F-gene and essential hypertension. 3. The relative risk of essential hypertens...

E ective social and emotional functioning is essential to healthy relationships at any age. Although the understanding of socioemotional functioning in late life has increased in recent decades, most of the existing research relies on information reported by individuals on questionnaires or during interviews. Social neuroscience promises to uncover important and novel information that can great...