Toluene is a commonly used volatile organic chemical in industry and is the most often chosen illicit substance among volatile substance abusers. Studies involving healthy volunteers suggest that ethanol consumption inhibits toluene metabolism, thus increasing its blood levels. In this study, a lethal case of combined ethanol consumption and toluene inhalation has been reported. Our case was a ...

This study was conducted to evaluate the prophylactic effect of ginger extract on ethanol-induced reproductive toxicity in male rats. Twenty-eight adult male Sprague-Dawley rats were randomly divided into 4 groups and treated daily for 28 days as follows: control, control-ginger (1 g/kg of body weight [BW]/day by gavage), ethanol group (ethanol 4 g/kg of BW/day by gavage), and ginger-ethanol gr...

Low ethanol tolerance is a crucial factor that restricts the feasibility of bioethanol production in renewable cyanobacterial systems. Our previous studies showed that several transcriptional regulators were differentially regulated by exogenous ethanol in Synechocystis. In this study, by constructing knockout mutants of 34 Synechocystis putative transcriptional regulator-encoding genes and ana...

The objective of this study was the investigation of a potential influence of artichoke leaf extract (ALE) on the cell physiology and gene expression of phase I/II enzymes of human liver cells HepG2 and investigation on potential cell protective effects against ethanol-induced cell toxicity against HepG2 cells. Cell biological assays under in vitro conditions using HepG2 liver cells and investi...

The increased probability of groundwater contamination by ethanol-blended fuel calls for improved understanding of how remediation efforts affect the fate and transport of constituents of concern, including the generation and fate of fermentation byproducts. A pilot-scale (8 m³) model aquifer was used to investigate changes in the concentrations of ethanol and its metabolites (methane and volat...

BACKGROUND Dysmorphology and dysfunction caused by prenatal ethanol consumption in different organs of the offspring are wellknown phenomena. The objective of the present study was to explore the antioxidant effect of vitamin E supplementation on testis damage induced by maternal ethanol consumption during pregnancy and early postnatal days. METHODS Pregnant Wistar rats on gestation day 7 wer...

Ethylene glycol (EG) is a toxic substance and EG metabolites cause metabolic acidosis. The major emphasis in this study to get rid of the toxicity before conversion its metabolites. interaction between ethylene ethanol has been studied using DFT (Density functional theory method). In blood; Glycolic acid more stable gloxal less stable. with considered for metabolism. Thermodynamic values obtain...