Sustained release is highly desired for “efficacious, safe and convenient” drug delivery, particularly those anticancer molecules with toxicity. In this study, a modified coaxial electrospraying process was developed to coat hydrophobic lipid, i.e., stearic acid (SA), on composites composed of the tamoxifen citrate (TC) insoluble polymeric matrix ethylcellulose (EC). Compared electrosprayed TC-...

the main objective of the present study was to formulate gastroretentive effervescent sustained release drug delivery systems of risperidone floating tablets with the help of methocel® k15, ethocel® standard 7fp premium, eudragit ® rs100 sustained release polymers to improve its safety profile, bioavailability and patient compliance. risperidone floating tablets were formulated by wet granulati...

The use of polymer latexes as vehicles for drug transport and controlled delivery in the body is a very active research field in applied colloid science. In this work, the polymer chosen is a commercially available ethylcellulose-based material, Aquacoat. We report electrokinetic (electrophoresis) data on this polymer in the presence of the soluble glucocorticoid betamethasone disodium phosphat...

the objective of this study was to formulate and evaluate the drug-polymer interaction of mefenamic acid (ma) using two polymers with different characteristics as ethylcellulose (ec) and/or cellulose acetate phthalate (cap). microspheres were prepared by the modified emulsion solvent evaporation (mese). the effect of drug-polymer interaction was studied for each of microspheres. important param...

The rheological properties, structure and phase transitions of hydroxypropyl cellulose in ethanol, dimethyl sulfoxide, ethylene glycol solutions ethylcellulose dimethylformamide are studied using viscometry, the cloud-point method, polarization microscopy, optical interferometry a photoelectric apparatus temperature range 280-360 K. temperature-concentration regions isotropic anisotropic phases...