The present study employed multivariate genetic item-level analyses to examine the ontology and the genetic and environmental etiology of the Big Five personality dimensions, as measured by the NEO Five Factor Inventory (NEO-FFI) [Costa and McCrae, Revised NEO personality inventory (NEO PI-R) and NEO five-factor inventory (NEO-FFI) professional manual, 1992; Hoekstra et al., NEO personality que...

BACKGROUND AND METHODS Fatal familial insomnia (FFI) is a rare genetic disease characterized by intractable insomnia, dysautonomia, and dementia. Herein we describe a patient with FFI. In order to study brain glucose hypometabolism in the patient, we used statistical parametric mapping (SPM) analysis of [(18)F]-fluorodeoxyglucose positron emission tomography (FDG-PET). CASE REPORT The patient...

OBJECTIVE Studying the thalamic role in the cortical expression of the Sleep Slow Oscillation (SSO) in humans by comparing SSO features in a case of Fatal Familial Insomnia (FFI) and a group of controls. METHODS We characterize SSOs in a 51-year-old male with FFI carrying the D178N mutation and the methionine/methionine homozygosity at the polymorphic 129 codon of the PRNP gene and in eight g...

BACKGROUND Intra-articular anesthetic drug injections are claimed to confirm the localization of the pain in order to treat the pain. The aim of the present study was to evaluate whether a positive effect of injection could be indicative for a successful outcome of future arthrodesis. METHODS 74 Patients underwent fluoroscopically guided and contrast confirmed anesthetic joint injections for ...

A growing number of libraries written in managed languages, such as Python and JavaScript, are bringing about new demand for a foreign language interface (FFI) between two languages. Such an FFI allows host-language program to seamlessly call library function exchange objects. It is often implemented by user-level but implementation cannot reclaim cyclic garbage, or group objects with circular ...

Approximately half of the variation in wellbeing measures overlaps with variation in personality traits. Studies of non-human primate pedigrees and human twins suggest that this is due to common genetic influences. We tested whether personality polygenic scores for the NEO Five-Factor Inventory (NEO-FFI) domains and for item response theory (IRT) derived extraversion and neuroticism scores pred...

The numerical solution of large scale multi-dimensional convection diffusion equations often requires efficient parallel algorithms. In this work, we consider the extension of a recently proposed non-overlapping domain decomposition method for two dimensional time dependent convection diffusion equations with variable coefficients. By combining predictor-corrector technique, modified upwind dif...

In this paper, a fuzzy frequent itemset (FFI)-Miner algorithm is developed to mine the complete set of FFIs without candidate generation. It uses a novel fuzzy-list structure to keep the essential information for later mining process. An efficient pruning strategy is also developed to reduce the search space, thus speeding up the mining process to directly discover the FFIs. Experiments are con...