PURPOSE To report outcomes on 5 patients treated with salvage partial low-dose-rate (LDR) 125-iodine ((125)I) permanent prostate seed brachytherapy (BT) for biopsy-proven locally persistent prostate cancer, following failure of dose-escalated external beam radiotherapy (EBRT). MATERIAL AND METHODS A retrospective review of the Fox Chase Cancer Center prostate cancer database identified five p...

INTRODUCTION Electron spin resonance (ESR) dosimetry using dental enamel is expected to be applicable to individual dose assessments, in the case where no dose information can be obtained from dosimeters, such as radiation accident. This method is based on the assumption of the linear relation between intensity of ESR signal induced by CO3 radicals and the absorbed dose in dental enamel. The ES...

BACKGROUND The aim of this paper was to report definitive outcome of prostate cancer patients treated with dose escalation during a period of 12.5 years. METHODS From October 1999 to March 2012 we treated 1080 patients affected by prostate cancer, using External Beam Radiotherapy (EBRT). The mean age was 69.2 years. Most of the patients (69%) were staged as cT2, Gleason Score (GS)<7; the mean...

 Abstract Background: Adjacent treatment fields are commonly used in external beam radiation therapy, such as mantle and inverted-Y fields for the treatment of Hodgkin’s disease and craniospinal fields used in the treatment of medulloblastoma and head and neck tumors when the lateral neck fields are placed adjacent to the anterior supraclavicular field. In each of these situations, there is a p...

Reported doses of external beam radiotherapy and radioimmunotherapy (RIT) to produce equivalent therapeutic effects are inconsistent, with many proposed causes. Calculations of effective dose were performed for the case of LS174T human colon cancer xenografts, where a 60Co single fraction exposure (6 Gy) was matched with 131I-labeled 17-1A monoclonal antibody therapy (300 microCi injection, 19 ...