Our previous studies have shown that hydrostatic pressure can serve as an active regulator for bone marrow mesenchymal stem cells (BMSCs). The current work further investigates the roles of cytoskeletal regulatory proteins Ras homolog gene family member A (RhoA) and Ras-related C3 botulinum toxin substrate 1 (Rac1) in hydrostatic pressure-related effects on BMSCs. Flow cytometry assays showed t...

Usually, dam monitoring systems are based on both boundary conditions (temperature, rainfall, water level, etc.) and structural responses (displacements, rotations, pore pressures, etc.). Statistical analysis tools are widely used to compare the current response of the dam with a whole set of recorded data, in order to determine eventual unwanted behaviors. The main drawback of this approach is...

Quantification of the permeability of connective tissue linings isolated from implanted capsules was achieved by two types of experiments. The objective of the first type was to determine the restriction offered by the lining to diffusion of 'I-labeled human serum albumin. The restricted diffusion coefficient of albumin with respect to the connective tissue lining the luminal capsule surface (i...

Theoretical studies have assumed that the hydrostatic pressure in anaerobic digesters is likely to have a negatively influence on the effectiveness of the biochemical processes in the bioreactors and consequently on the biogas production. These assumptions made the authors approach this interesting topic and carry on experimental studies aimed to reveal the methanogens response on the hydrostat...

Quantification of the permeability of connective tissue linings isolated from implanted capsules was achieved by two types of experiments. The objective of the first type was to determine the restriction offered by the lining to diffusion of 125I-labeled human serum albumin. The restricted diffusion coefficient of albumin with respect to the connective tissue lining the luminal capsule surface ...

An antibubble is a spherical air film that is immersed in a surfactant mixture and drains under the action of hydrostatic pressure. A dynamical model of this film is proposed that accounts for the surface shear viscosity effects in the case of purely viscous interfaces, which applies for surfactants whose adsorption rate is much larger than advection rate and at a concentration much above the c...

Following an approach initially outlined by McKee & Holliman [5], we investigate the structure and stability of dense, starless molecular cloud cores. We model those as spherical clouds in hydrostatic equilibrium and supported against gravity by thermal, turbulent, and magnetic pressure. We determine the gas pressure by solving for thermal equilibrium between heating and cooling, while the turb...

Optic nerve head astrocytes become abnormal in eyes that have elevated intraocular pressure, and cultured astrocytes display altered protein expression after being subjected for > or = 1 days to elevated hydrostatic pressure. Here we show that 2-h elevated hydrostatic pressure (15 or 30 mmHg) causes phosphorylation of ERK1/2, ribosomal S6 protein kinase (p90(RSK)), and Na/H exchanger (NHE)1 in ...

The pressure-dependence of the hidden order phase transition of URu2Si2 is shown to depend sensitively upon the quality of hydrostatic pressure conditions during electrical resistivity measurements. Hysteresis in pressure is demonstrated for two choices of pressure medium: the commonly-used mixture of 1:1 Fluorinert FC70/FC77 and pure FC75. In contrast, no hysteresis is observed when the pressu...

BACKGROUND Glaucoma is a progressive optic neuropathy characterized by degeneration of neurons due to loss of retinal ganglion cells (RGCs). High intraocular pressure (HIOP), the main risk factor, causes the optic nerve damage. However, the precise mechanism of HIOP-induced RGC death is not yet completely understood. This study was conducted to determine apoptosis of RGC-5 cells induced by elev...