Gene targeting studies revealed that Dicer1 is required for murine embryogenesis.In this issue of Blood, Alemdehy and colleagues examine deletion of Dicer1 in myeloid progenitor cells using a conditional Cebpa-Cre allele. They show that deletion of Dicer1 is required for viability and that Dicer1 regulates steps of neutrophil maturation.

Finite field multiplier is widely applied in many domains such as coding theory and cryptography. In this paper, it is purposed to propose a concurrent all-cell error detection semi-systolic polynomial basis multiplier based on coding theory which can realize high-speed calculation and high efficient error detection with low resource consumption. First, our method is created to choose an apprec...

In this paper, a basic framework for efficient scalable video coding, namely progressive fine granularity scalable (PFGS) video coding is proposed. Similar to the fine granularity scalable (FGS) video coding in MPEG-4, the PFGS framework has all the features of FGS, such as fine granularity bit-rate scalability, channel adaptation, and error recovery. On the other hand, different from the FGS c...

Link failures in wide area networks are common and cause significant data losses. Mesh-based protection schemes offer high capacity efficiency but they are slow and require complex signaling. Additionally, real-time reconfigurations of crossconnects threaten their transmission integrity. On the other hand, there are other schemes that are proactive. Proactivity results in higher restoration spe...

BACKGROUND Peroxisome proliferator-activated receptor gamma (PPARG), CCAAT/enhancer binding protein alpha (CEBPA) and retinoid X receptor alpha (RXRA) are nuclear transcription factors that play important roles in regulation of adipogenesis and fat deposition. The objectives of this study were to characterise the variability of these three candidate genes in a mixed sample panel composed of sev...

Efficient video transmission over unreliable channels may encounter huge challenge due to unavoidable bit error or packets loss. Error concealment (EC) techniques at the decoder side have been developed to recover the damaged regions utilizing spatial or temporal redundant information without changing the encoder structure or adding extra bandwidth. In this work the classic EC techniques and th...

BACKGROUND To identify potential molecular prognostic markers in core binding factor (CBF) AML, we analyzed incidences and prognostic impacts of mutations in c-KIT, WT1, CEBPA, CBL, and a number of epigenetic genes in CBF AML. METHODS Seventy one and 21 AML patients with t(8;21) and inv(16) were enrolled in this study, respectively. NPM1, CEBPA, c-KIT, IDH1/2, DNMT3A, EZH2, WT1, and CBL mutat...